Protein Alignment Gat and slc6a11b

DIOPT Version :10

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_073772263.1
• Gene: slc6a11b / 100150472
• ZFINID: ZDB-GENE-121116-2
• Length: 617
• Species: Danio rerio
• Alignment Length: 591
• Identity: 303/591 - (51%)
• Similarity: 405/591 - (68%)
• Gaps: 33/591 - (5%)

  Fly    34 QSSSPTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFIL 98
            :|::|:.. .||.:::|.     :||.|::|::|:|||.|..|||||||||||||||||||||.:
Zfish    21 ESANPSVV-RSNDKKVVN-----ERGQWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFV 79

  Fly    99 PYIITLFLAGIPMFFMELALGQMLTIGGLGVF-KIAPIFKGIGYAAAVMSCWMNVYYIVILAWAV 162
            ||:|.....|||:||:|.||||..:.||:..: |:.|:|:|||||..|:...:||||:||||||:
Zfish    80 PYVIFFVCCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYVVILAWAI 144

  Fly   163 FYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPV 227
            ||.|.....::||.:|.::|||.|||.             .|       :.|..|.|:...|.||
Zfish   145 FYLFNCFTTELPWASCGHYWNTENCVD-------------FN-------NESIANFTNPYSTSPV 189

  Fly   228 KEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTIL 292
            .||||||.|:||.||||:|.:|||||..|.:.|::||||||||.|.||||||.||.|||.:|.||
Zfish   190 MEFWERRVLKISSGIEEVGGLRWELALCLAIAWVICYFCIWKGPKSTGKVVYVTATFPYFMLLIL 254

  Fly   293 LVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKD 357
            |:||||||||..|||||:.|:.|:|::.:||:||.|||||||.:.||.|.||||||.:.||.|:|
Zfish   255 LLRGITLPGAANGIKFYLYPDISRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNSYNNNCYRD 319

  Fly   358 ALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCL 422
            .|::|.:||.||..|||.||||:||||:||..|:..||.|||||||:.||.||..:|.:|:|:.|
Zfish   320 CLMLCCLNSGTSFVAGFAIFSVLGFMAYEQNVPIEAVAESGPGLAFIAYPKAVTMMPWAPLWAAL 384

  Fly   423 FFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLR--KRKEIFIAIVCALSYLVGLTCITQGGMYIF 485
            ||.||:.:||||||..:|..:|||:|.:|:..|  .|:|:.|..:...|:.:||..:|:||||:|
Zfish   385 FFMMLIFLGLDSQFVCVESLVTAIVDMYPKTFRVGYRRELLILGMSIASFFLGLIMLTEGGMYVF 449

  Fly   486 QILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVF 550
            |:.||||.||.|||::..||.:.|.|.||.||||..|:|||||.|..:.|:||...||.||.|:|
Zfish   450 QLFDSYAASGMCLLFVAIFESICIGWVYGSDRFYMNIEDMIGYKPIFFIKWCWKFFTPGICTGIF 514

  Fly   551 FFNIVQWTPVKYLD-YSYPWWAHAFGWFTALSSMLYIPL-YMFWLWKRTPGELSEKIRALVRIDE 613
            .|.::::.|:||.: |:||.|.:..||..|:|||:.||| .:|.:|| |.|...|:|:.|.....
Zfish   515 LFFLIKYKPLKYNNVYTYPDWGYGIGWMMAMSSMVCIPLGILFQIWK-TKGTFRERIKKLTTPSA 578

  Fly   614 DVTRLR 619
            |: |:|
Zfish   579 DL-RMR 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	295/557 (53%)
slc6a11b	XP_073772263.1	None