Protein Alignment Gat and slc6a8l

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_012815966.1
• Gene: slc6a8l / 100127575
• XenbaseID: XB-GENE-5768780
• Length: 654
• Species: Xenopus tropicalis
• Alignment Length: 562
• Identity: 296/562 - (52%)
• Similarity: 398/562 - (70%)
• Gaps: 14/562 - (2%)

  Fly    50 VKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFM 114
            ||| .:|:|.:|:.:||||:|.||.|:||||||||||||||||||.|::||::.:|:.|||:||:
 Frog    54 VKI-PIPERETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYLLIVFVGGIPVFFL 117

  Fly   115 ELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCN 179
            |:||||.:..||:..:.|||:|||:|:|:.|:..:.|.|||:||.|.::|...|....:||.||.
 Frog   118 EIALGQFMKQGGIAAWNIAPLFKGLGFASMVIVFFCNTYYIMILVWGLYYLVHSFTNTLPWATCG 182

  Fly   180 NWWNTVNCVSQYERKNLHCWDKIINGTTQKVC-SVSALNITSLELTD---PVKEFWERRALQISH 240
            |.||:..|...:...  ||    .||:...|. |.:.:||:...|.:   ||.|||||:.||||.
 Frog   183 NPWNSKECTEVFLVD--HC----NNGSLANVTDSGTLVNISCDALVNKRSPVIEFWERKVLQISG 241

  Fly   241 GIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEG 305
            |:.|.|.:.|::...|:..|::.|||||||||.||||||||||||||:|.:||..|:||||||:|
 Frog   242 GLNEPGQLNWQMILCLMATWVIVYFCIWKGVKSTGKVVYFTALFPYVVLIVLLAHGVTLPGALDG 306

  Fly   306 IKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSM 370
            |.:|:.||:|||..::|||||.|||||||.:|||.|.||||||:|.||.|:||.|:..:||:||.
 Frog   307 IVYYLKPNWSKLAEAQVWIDAGTQIFFSYAIGLGALTALGSYNRFHNNCYRDAYILAAINSTTSF 371

  Fly   371 FAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQ 435
            |||||:|||:||||.||...::.||.|||||||:.||.||..:|.:|:|:.|||||||::|||||
 Frog   372 FAGFVVFSVLGFMASEQGVHISKVAESGPGLAFIAYPKAVTLMPFAPIWAALFFFMLLILGLDSQ 436

  Fly   436 FCTMEGFITAIIDEWPQLLR--KRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCL 498
            |..:|||||.|:|.:||.:.  .|:|:..|:.|.:.:::.|:.:|:||||:||:.|.|:.||..|
 Frog   437 FVGVEGFITGIMDLFPQPINGFVRREVTAALCCLVCFIIDLSMVTEGGMYVFQLFDYYSASGITL 501

  Fly   499 LWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKY- 562
            ||..|:|||.|:|.||.|||.|.|..||||.|..:.|:||.|.||.:|:|:|.|::|.:.|:.|
 Frog   502 LWQAFWECVVIAWVYGADRFMDDIARMIGYRPLPYMKWCWSVLTPLVCVGIFVFHVVNYKPLTYN 566

  Fly   563 LDYSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRTPGELSEK 604
            ..|.||||..|.||..||:|||.|||.:.....|:.|.|.|:
 Frog   567 KSYVYPWWGEAIGWSLALASMLCIPLTVVCKMLRSKGSLRER 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	292/554 (53%)
slc6a8l	XP_012815966.1	SLC6sbd_CT1	61..654	CDD:271397	292/554 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145627at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020