DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gat and si:ch211-132b12.3

DIOPT Version :9

Sequence 1:	NP_651930.2	Gene:	Gat / 43805	FlyBaseID:	FBgn0039915	Length:	636	Species:	Drosophila melanogaster
Sequence 2:	NP_001076419.1	Gene:	si:ch211-132b12.3 / 100002232	ZFINID:	ZDB-GENE-050419-161	Length:	577	Species:	Danio rerio

Alignment Length:	538	Identity:	257/538 - (47%)
Similarity:	364/538 - (67%)	Gaps:	22/538 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 QLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELAL 118
            |..:||.|..|.:|:|:|.|..:|:|||||||||||:||||.|::||::.:...|:|:|.:|..:
Zfish     7 QTEERGFWGRKAEFLLAVAGNVVGVGNVWRFPYLCYRNGGGVFLIPYLVFVMTCGVPLFLLETVM 71

  Fly   119 GQMLTIGGLGVFK-IAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWW 182
            ||....||:..:. :.|:.:|:|||..::..:..:|:.:|||||:||...|..:.:||.:|:|.|
Zfish    72 GQFTHEGGITCWHLLCPLAQGVGYAGQLIELYSCMYFTIILAWALFYLIFSFSSQLPWASCDNIW 136

  Fly   183 NTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWERRALQISHGIEEIGN 247
            ||.|||      ||...:...|.|||       :|.||     ...||||||.|.:|.||||||.
Zfish   137 NTDNCV------NLAAGNLTFNRTTQ-------INSTS-----AATEFWERRVLSLSGGIEEIGK 183

  Fly   248 IRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIP 312
            |.||:|..|.::||:||||||||||.|||||||||.||||:|.:||:||:||||||:|:.||:.|
Zfish   184 INWEIALCLFVMWIICYFCIWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFYLYP 248

  Fly   313 NFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIF 377
            ..:.|.:.:||::|.||:||||.|..|.|:||||||:::||.|:|:..:|.:||.||..|||.:|
Zfish   249 EPAHLADPQVWMEAGTQVFFSYSLCSGILIALGSYNQYSNNCYRDSFWLCLLNSGTSFVAGFAVF 313

  Fly   378 SVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGF 442
            ||:|||||.|..||.:||.|||||||:.||.||..:|...:|:..||.|::|:||||||..||..
Zfish   314 SVLGFMAHVQGVPVEEVAESGPGLAFIAYPQAVAMMPFPQLWAVCFFIMIILLGLDSQFVAMECV 378

  Fly   443 ITAIIDEWPQLLRK--RKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFE 505
            :|::.|.:|::||:  |:|:|:.::|...:...|..:|:||||:||:.|:||.:|.|.|:|..||
Zfish   379 VTSVTDLFPEVLRRAGRRELFVLLLCLTCFFGQLIMVTEGGMYVFQLFDNYASNGACFLFLSVFE 443

  Fly   506 CVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLD-YSYPW 569
            .::|.|.:|.::.:|.||||....|..|:..||...||.:.|..|.:::|::||:.|.. |.||.
Zfish   444 SLTIGWIFGAEKMFDIIKDMTESRPNYWFMLCWKYLTPLVSLTSFVYSMVRYTPLTYNRWYVYPD 508

  Fly   570 WAHAFGWFTALSSMLYIP 587
            |||..||..||||:|.:|
Zfish   509 WAHVLGWLLALSSILLVP 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	256/534 (48%)
si:ch211-132b12.3	NP_001076419.1	SLC6sbd-TauT-like	11..550	CDD:271387	256/534 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145627at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100347
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.820