Protein Alignment mav and GDF3

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_065685.1
• Gene: GDF3 / 9573
• HGNCID: 4218
• Length: 364
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 60/227 - (26%)
• Similarity: 95/227 - (41%)
• Gaps: 50/227 - (22%)

  Fly   482 IEFDVTKAVRSWLNKSHENLG--IEIQCDKCKSIGARILSDFSP-STPPRSTASSDEHLNLMPVL 543
            :.|::....:.|.:...:|.|  :||...:.:..|.    :|.| .|..|...|.  |.:|:.|
Human   179 VHFNLLDVAKDWNDNPRKNFGLFLEILVKEDRDSGV----NFQPEDTCARLRCSL--HASLLVV- 236

  Fly   544 NIIGHGTLNSQQHGDADIHQIMLTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQR--CCRNQL 606
                  |||..|                        .|.|  ||.:......||..:  |.|:||
Human   237 ------TLNPDQ------------------------CHPS--RKRRAAIPVPKLSCKNLCHRHQL 269

  Fly   607 DVAFKSIKGFEFILQPKVFDAGYCHGRCP---PRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSK 668
            .:.|:.:...::|:.||.|.|.||||.||   .....:.::|.:|:|:...| ...|:..|.|:|
Human   270 FINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVD-PEIPQAVCIPTK 333

  Fly   669 LEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
            |..:.:|:.|.|  |.:.:..:.||.|.||.|
Human   334 LSPISMLYQDNN--DNVILRHYEDMVVDECGC 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	5/25 (20%)
		TGF_beta	599..700	CDD:278448	34/105 (32%)
GDF3	NP_065685.1	TGFb_propeptide	<109..220	CDD:279078	9/44 (20%)
		TGFB	264..364	CDD:214556	35/103 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810