Protein Alignment mav and GDF15

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_004855.2
• Gene: GDF15 / 9518
• HGNCID: 30142
• Length: 308
• Species: Homo sapiens
• Alignment Length: 102
• Identity: 22/102 - (21%)
• Similarity: 48/102 - (47%)
• Gaps: 4/102 - (3%)

  Fly   600 RCCR-NQLDVAFKSIKGFEFILQPKVFDAGYCHGRCPPRHNPAHHHALLQSLIWQEDHKRAPRPC 663
            |||| :.:..:.:.:...:::|.|:......|.|.||.:...|:.||.:::.:.:......|.||
Human   209 RCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPSQFRAANMHAQIKTSLHRLKPDTVPAPC 273

  Fly   664 CTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
            |.|:....:.::   :.....:.:.|:.|:...:|.|
Human   274 CVPASYNPMVLI---QKTDTGVSLQTYDDLLAKDCHC 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078
		TGF_beta	599..700	CDD:278448	21/100 (21%)
GDF15	NP_004855.2	MscS_TM	<23..>147	CDD:331130
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	152..177
		TGFB	211..308	CDD:214556	20/100 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D338011at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820