DRSC/TRiP Functional Genomics Resources

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Protein Alignment mav and BMP15

DIOPT Version :9

Sequence 1:NP_524626.1 Gene:mav / 43804 FlyBaseID:FBgn0039914 Length:701 Species:Drosophila melanogaster
Sequence 2:NP_005439.2 Gene:BMP15 / 9210 HGNCID:1068 Length:392 Species:Homo sapiens


Alignment Length:260 Identity:56/260 - (21%)
Similarity:89/260 - (34%) Gaps:89/260 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   481 WIEFDVTKAV--RSWLNKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVL 543
            |.|.|:|:.|  |.|.||.|..|.:...|.:.|..|.                     |.|.   
Human   181 WKEMDITQLVQQRFWNNKGHRILRLRFMCQQQKDSGG---------------------LELW--- 221

  Fly   544 NIIGHGTLNSQQHGDADIHQIMLTNNRSDQYVHHRS---------------NHDSTWRKDKWT-- 591
                |||      ...||..::|..|.:     |:|               ..:|..|:.:..  
Human   222 ----HGT------SSLDIAFLLLYFNDT-----HKSIRKAKFLPRGMEEFMERESLLRRTRQADG 271

  Fly   592 ----------------NNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRC-----P 635
                            ||      :|..:...::|:.:....:|:.|..:...||.|.|     .
Human   272 ISAEVTASSSKHSGPENN------QCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRD 330

  Fly   636 PRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
            ..::|  :||::|:||.|...:..|||.|.|.|...:.:|.::.|.|  :....:..|....|.|
Human   331 GLNSP--NHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGS--ILYKEYEGMIAESCTC 391

  Fly   701  700
            Human   392  391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mavNP_524626.1 TGFb_propeptide <442..506 CDD:279078 11/26 (42%)
TGF_beta 599..700 CDD:278448 26/105 (25%)
BMP15NP_005439.2 TGF_beta 291..391 CDD:306518 26/103 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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