Protein Alignment mav and TGFB1

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: XP_011525544.1
• Gene: TGFB1 / 7040
• HGNCID: 11766
• Length: 391
• Species: Homo sapiens
• Alignment Length: 360
• Identity: 78/360 - (21%)
• Similarity: 128/360 - (35%)
• Gaps: 111/360 - (30%)

  Fly   360 EQDTMNILLHFPLTNAQDANFHHDKIDEANVRLMLLYSSSLATNFRRGPGSRKNKISQISGNDNI 424
            :|.|.:|.:.|..:..::|......:..|.:||:.|                  |:       .:
Human   125 KQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRL------------------KL-------KV 164

  Fly   425 ERHCNFGDVNLNQSNKNSSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRTQWIEFDVTKA 489
            |:|                    :::||..|.|..|.:::|.:.      .....:|:.||||..
Human   165 EQH--------------------VELYQKYSNNSWRYLSNRLLA------PSDSPEWLSFDVTGV 203

  Fly   490 VRSWLNKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQ 554
            ||.||::..|..|..:.                      :..|.|...|.:.|
Human   204 VRQWLSRGGEIEGFRLS----------------------AHCSCDSRDNTLQV------------ 234

  Fly   555 QHGDADIHQIMLTNNRSDQYVHH---------------RSNH--DSTWRKDKWTNNCY-KLHQRC 601
                 ||:....|..|.|....|               |:.|  .|..|:...||.|: ...:.|
Human   235 -----DINAGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNC 294

  Fly   602 CRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCPPRHNPAHHHALLQSLIWQEDHKRAPRPCCTP 666
            |..||.:.|:...|:::|.:||.:.|.:|.|.||...:....::.:.:|..|.:...:..|||.|
Human   295 CVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVP 359

  Fly   667 SKLEMLEILHVDENHSDKLKISTWSDMQVVECACS 701
            ..||.|.|::.   ...|.|:...|:|.|..|.||
Human   360 QALEPLPIVYY---VGRKPKVEQLSNMIVRSCKCS 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	17/63 (27%)
		TGF_beta	599..700	CDD:278448	30/100 (30%)
TGFB1	XP_011525544.1	TGFb_propeptide	30..262	CDD:395559	39/226 (17%)
		TGF_beta_TGFB1	293..391	CDD:381654	30/100 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1343
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810