Protein Alignment mav and BMP8B

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: XP_011540326.2
• Gene: BMP8B / 656
• HGNCID: 1075
• Length: 427
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 70/310 - (22%)
• Similarity: 121/310 - (39%)
• Gaps: 93/310 - (30%)

  Fly   443 SQQLTLKVYQLLSANRRRK-----ITSRKIEFGNVGFQETRTQWIEFDVTKAVRSWLNKSHENLG 502
            ::.|.:.::|::.....|:     :..:.:..|:.|       |:..|||.|...||.|.|::||
Human   158 NRTLHVSMFQVVQEQSNRESDLFFLDLQTLRAGDEG-------WLVLDVTAASDCWLLKRHKDLG 215

  Fly   503 I---------------------EIQCDKCK-SIGARILSDFSPSTPPRSTASSDEHLNLMPVLNI 545
            :                     .:|..|.: |....:||..:|. |.::.|.       .|:|.:
Human   216 LRLYVETEDGETWTGWGWTKDSRLQMWKLRLSRTPWVLSLHAPG-PAQAPAE-------RPLLCL 272

  Fly   546 IGHGTLNSQQHGDADIHQIMLTNNRSDQYVH-------HRSN---------------HDSTWRKD 588
            :       |.|..|....|     |:.:.|.       .:||               |.|..|
Human   273 L-------QGHCPASPSPI-----RTPRAVRPLRRRQPKKSNELPQANRLPGIFDDVHGSHGR-- 323

  Fly   589 KWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCP-PRHN--PAHHHALLQSL 650
                      |.|.|::|.|:|:.:...::::.|:.:.|.||.|.|. |..:  .|.:||:||||
Human   324 ----------QVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSL 378

  Fly   651 IWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
            :........|:.||.|:||....:|:.|.  |:.:.:....:|.|..|.|
Human   379 VHLMMPDAVPKACCAPTKLSATSVLYYDS--SNNVILRKHRNMVVKACGC 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	16/88 (18%)
		TGF_beta	599..700	CDD:278448	32/103 (31%)
BMP8B	XP_011540326.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910