Protein Alignment mav and BMP7

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001710.1
• Gene: BMP7 / 655
• HGNCID: 1074
• Length: 431
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 63/278 - (22%)
• Similarity: 120/278 - (43%)
• Gaps: 54/278 - (19%)

  Fly   443 SQQLTLKVYQLLSANRRRK-----ITSRKIEFGNVGFQETRTQWIEFDVTKAVRSWLNKSHENLG 502
            ::...:.|||:|..:..|:     :.||.:.....|       |:.||:|.....|:.....|||
Human   187 NETFRISVYQVLQEHLGRESDLFLLDSRTLWASEEG-------WLVFDITATSNHWVVNPRHNLG 244

  Fly   503 IEIQCDKC--KSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIG-HGTLNSQQHGDA----- 559
            :::..:..  :||..::                         ..:|| ||..|.|....|
Human   245 LQLSVETLDGQSINPKL-------------------------AGLIGRHGPQNKQPFMVAFFKAT 284

  Fly   560 DIHQIMLTNNRSDQYVHHRS----NHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFIL 620
            ::|...:.:..|.|...:||    |.::....:...|:.....|.|.:::|.|:|:.:...::|:
Human   285 EVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWII 349

  Fly   621 QPKVFDAGYCHGRCPPRHNP---AHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHS 682
            .|:.:.|.||.|.|....|.   |.:||::|:|:...:.:..|:|||.|::|..:.:|:.|:  |
Human   350 APEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDD--S 412

  Fly   683 DKLKISTWSDMQVVECAC 700
            ..:.:..:.:|.|..|.|
Human   413 SNVILKKYRNMVVRACGC 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	16/67 (24%)
		TGF_beta	599..700	CDD:278448	30/103 (29%)
BMP7	NP_001710.1	TGFb_propeptide	35..280	CDD:366248	24/124 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..311		5/19 (26%)
		TGF_beta_BMP7	325..431	CDD:381667	31/108 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910