Protein Alignment mav and BMP5

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_066551.1
• Gene: BMP5 / 653
• HGNCID: 1072
• Length: 454
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 75/347 - (21%)
• Similarity: 144/347 - (41%)
• Gaps: 51/347 - (14%)

  Fly   371 PLTNAQDANFHHDKIDEANVRLMLLYSSSLATNFRRGPGSRKNKISQISGNDNIERHCNFGDVNL 435
            ||.:..|.||.:| .|.....:.|:......::.||.....:..::||...:.:.. ..|.....
Human   141 PLASLHDTNFLND-ADMVMSFVNLVERDKDFSHQRRHYKEFRFDLTQIPHGEAVTA-AEFRIYKD 203

  Fly   436 NQSNKNSSQQLTLKVYQLLSANRRRK-----ITSRKIEFGNVGFQETRTQWIEFDVTKAVRSWLN 495
            ..:|:..::.:.:.:||::.....|.     :.:||.:..:||       |:.||:|.....|:.
Human   204 RSNNRFENETIKISIYQIIKEYTNRDADLFLLDTRKAQALDVG-------WLVFDITVTSNHWVI 261

  Fly   496 KSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQ----- 555
            ....|||:::    |...|                  ....:|:... .::|.....|:|
Human   262 NPQNNLGLQL----CAETG------------------DGRSINVKSA-GLVGRQGPQSKQPFMVA 303

  Fly   556 ---HGDADIHQIMLTNNRSDQYVHHRSNH-DSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGF 616
               ..:..:..:...|.|.:|..:..|:| ||:........|..:..|.|.:::|.|:|:.:...
Human   304 FFKASEVLLRSVRAANKRKNQNRNKSSSHQDSSRMSSVGDYNTSEQKQACKKHELYVSFRDLGWQ 368

  Fly   617 EFILQPKVFDAGYCHGRCP---PRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVD 678
            ::|:.|:.:.|.||.|.|.   ..|..|.:||::|:|:........|:|||.|:||..:.:|:.|
Human   369 DWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKPCCAPTKLNAISVLYFD 433

  Fly   679 ENHSDKLKISTWSDMQVVECAC 700
            :  |..:.:..:.:|.|..|.|
Human   434 D--SSNVILKKYRNMVVRSCGC 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	15/68 (22%)
		TGF_beta	599..700	CDD:278448	31/103 (30%)
BMP5	NP_066551.1	TGFb_propeptide	32..304	CDD:395559	35/194 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..343		7/24 (29%)
		TGF_beta_BMP5	342..454	CDD:381665	33/114 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910