Protein Alignment mav and BMP3

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001192.4
• Gene: BMP3 / 651
• HGNCID: 1070
• Length: 472
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 98/453 - (21%)
• Similarity: 155/453 - (34%)
• Gaps: 170/453 - (37%)

  Fly   383 DKIDEANVRLMLLYSSSLATNFRRGPGSRKNKISQISGNDNIERHCNFGDVNLNQSNKNSS---- 443
            ||:.|..:||...||:..|.   |.|||       :.|.....|.....:.|..:|.:.::
Human    54 DKVSEHMLRLYDRYSTVQAA---RTPGS-------LEGGSQPWRPRLLREGNTVRSFRAAAAETL 108

  Fly   444 QQLTLKVYQLLSANRRRKITSRKI-----EFGNVG----------------------------FQ 475
            ::..|.::.|.|..:...|.|..:     |.||:.                            |.
Human   109 ERKGLYIFNLTSLTKSENILSATLYFCIGELGNISLSCPVSGGCSHHAQRKHIQIDLSAWTLKFS 173

  Fly   476 ETRTQ------------------WIEFDVTKAVRSWLNKSHEN----LGIEIQCDKCKSIGAR-- 516
            ..::|                  |:..|:|:.:|    |:.||    :|..| ..|.:.:..|
Human   174 RNQSQLLGHLSVDMAKSHRDIMSWLSKDITQLLR----KAKENEEFLIGFNI-TSKGRQLPKRRL 233

  Fly   517 --------ILSDFSPSTPPRSTASS---------------DEHLN---------------LMPVL 543
                    :.::.:..:.|.|..||               |.|:.               |:|:.
Human   234 PFPEPYILVYANDAAISEPESVVSSLQGHRNFPTGTVPKWDSHIRAALSIERRKKRSTGVLLPLQ 298

  Fly   544 N--IIG----------------HGTLNSQQHGDADIHQIMLTNNRSDQYVHHRSNHDSTW----- 585
            |  :.|                :.||.:|....:       .|.:..:...||.:....:
Human   299 NNELPGAEYQYKKDEVWEERKPYKTLQAQAPEKS-------KNKKKQRKGPHRKSQTLQFDEQTL 356

  Fly   586 ---RKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCP---PRHNPAHHH 644
               |:.:|..     .:.|.|..|.|.|..|...|:|:.||.|||.||.|.|.   |:.....:|
Human   357 KKARRKQWIE-----PRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNH 416

  Fly   645 ALLQSLIWQEDHKRA-------PRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
            |.:||::      ||       |.|||.|.|:..|.||..|||.:..||:  :.:|.|..|||
Human   417 ATIQSIV------RAVGVVPGIPEPCCVPEKMSSLSILFFDENKNVVLKV--YPNMTVESCAC 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	18/122 (15%)
		TGF_beta	599..700	CDD:278448	41/110 (37%)
BMP3	NP_001192.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..53
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	320..350		6/36 (17%)
		TGF_beta_BMP3	363..472	CDD:381663	44/122 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810