Protein Alignment mav and Tgfb1

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_067589.1
• Gene: Tgfb1 / 59086
• RGDID: 69051
• Length: 390
• Species: Rattus norvegicus
• Alignment Length: 270
• Identity: 78/270 - (28%)
• Similarity: 121/270 - (44%)
• Gaps: 51/270 - (18%)

  Fly   442 SSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRT-QWIEFDVTKAVRSWLNKSHENLGIEI 505
            |:.:..:::||..|.|..|.:       ||.....|.| :|:.||||..||.|||:..   ||:
  Rat   162 STVEQHVELYQKYSNNSWRYL-------GNRLLTPTDTPEWLSFDVTGVVRQWLNQGD---GIQ- 215

  Fly   506 QCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQHGD-ADIHQ------ 563
                    |.|    ||      :..|.|...|   ||::..:| ::.::.|| ..||.
  Rat   216 --------GFR----FS------AHCSCDSKDN---VLHVEING-ISPKRRGDLGTIHDMNRPFL 258

  Fly   564 -IMLTNNRSDQYVHHRSNHDSTWRKDKWTNNCY-KLHQRCCRNQLDVAFKSIKGFEFILQPKVFD 626
             :|.|.....|:: |.|.|    |:...||.|: ...:.||..||.:.|:...|:::|.:||.:.
  Rat   259 LLMATPLERAQHL-HSSRH----RRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYH 318

  Fly   627 AGYCHGRCPPRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWS 691
            |.:|.|.||...:....::.:.:|..|.:...:..|||.|..||.|.|::.   ...|.|:...|
  Rat   319 ANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQALEPLPIVYY---VGRKPKVEQLS 380

  Fly   692 DMQVVECACS 701
            :|.|..|.||
  Rat   381 NMIVRSCKCS 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	24/76 (32%)
		TGF_beta_maverick	598..700	CDD:381633	30/101 (30%)
Tgfb1	NP_067589.1	TGFb_propeptide	30..261	CDD:459906	36/131 (27%)
		Straightjacket domain. /evidence=ECO:0000250|UniProtKB:P07200	30..74
		Arm domain. /evidence=ECO:0000250|UniProtKB:P07200	75..271		39/141 (28%)
		Bowtie tail. /evidence=ECO:0000250|UniProtKB:P01137	226..252		8/29 (28%)
		Cell attachment site. /evidence=ECO:0000255	244..246		0/1 (0%)
		TGF_beta_TGFB1	292..390	CDD:381654	30/100 (30%)