Protein Alignment mav and gdf9

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001012383.1
• Gene: gdf9 / 497643
• ZFINID: ZDB-GENE-050221-7
• Length: 418
• Species: Danio rerio
• Alignment Length: 375
• Identity: 82/375 - (21%)
• Similarity: 147/375 - (39%)
• Gaps: 81/375 - (21%)

  Fly   381 HHDKIDEANVRLM-LLYSSSLATNFRRGPGSRKNKISQI--SGNDNIERHCNFGDVNLNQS-NKN 441
            |..|.|...||.| .||..| :..:|....|.....:::  ...:.::::..|...:::.| |:.
Zfish    69 HRTKPDSRYVRYMRRLYKQS-SKPYRSPEASHLYNTARLITPREECLKQNREFFMQDISYSLNRV 132

  Fly   442 SSQQLTLKVYQLLSAN---------------RRRKITSRKIEFGNVGFQET--------RTQWIE 483
            .||:..||...|.|.:               :.:|.:..::...::|.|.:        ..:|:|
Zfish   133 RSQEHLLKSVLLYSFDHNHLSPFSLLCYLDMKEQKSSKDQMCSNHLGIQHSVPLLSFRVHHRWVE 197

  Fly   484 FDVTKAVRSWL--NKSHENLGIEIQC--DKCKSIGARILS---DFSPSTPPRSTASSDEHLNLMP 541
            .|||..:...:  :|...:|.|.:.|  |.....|.:|..   :.:|.:|           :|:.
Zfish   198 VDVTSFLHPLIQAHKKDIHLLINLTCVEDMISRPGGQIHKSPVELTPRSP-----------SLLL 251

  Fly   542 VLNIIGHGTLNSQQHGDADIHQIMLTNNRSDQYVHHRSNHDSTW----RKDKWT-----NNCYKL 597
            .||....   .:.|........:.||:|       |.....:.|    |:.:.|     .:..||
Zfish   252 YLNDTSE---VAYQRRSTQGRMVDLTSN-------HWDGKSTLWELTSRRRRGTLKSSETSMPKL 306

  Fly   598 -------HQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCPPR-----HNPAHHHALLQSL 650
                   ...|......|:||.:|...:|::||.::..||.|.||..     .:|.  |.::|:|
Zfish   307 VPMYEFTTDDCDLYDFRVSFKELKLDHWIIEPKKYNPRYCKGSCPRNVGFMYGSPM--HTMVQNL 369

  Fly   651 IWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
            |:::.....|||.|.||:...|.:|..:.:.|...|  .:.:|...:|||
Zfish   370 IYEKLDSSVPRPTCVPSEYNPLSVLTFENDKSYAYK--EYEEMIATKCAC 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	22/107 (21%)
		TGF_beta_maverick	598..700	CDD:381633	30/106 (28%)
gdf9	NP_001012383.1	TGF_beta_SF	313..418	CDD:477357	32/109 (29%)