Protein Alignment mav and gbb

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_477340.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Alignment Length: 530
• Identity: 121/530 - (22%)
• Similarity: 201/530 - (37%)
• Gaps: 143/530 - (26%)

  Fly   215 VQWINTVP--IQSRQTRETRDIGLETKRHSKPSKRVDETRLKHLVLKGLGIKKLPDMRKVNISQA 277
            :.::.|.|  :::.|:....|.|.:.....:.....|:..:.:.:|:.|||.:.|    .::|..
  Fly    24 LMFVATTPPAVEATQSGIYIDNGKDQTIMHRVLSEDDKLDVSYEILEFLGIAERP----THLSSH 84

  Fly   278 EYSSKYIEYLSRLRSNQEKGNSYFNNFMGASFTRDLHFLSITTNGFN--DISNKRLRHRRSLKKI 340
            :.|         ||.:..|            |..|::.......|.:  |..:...|..||.:..
  Fly    85 QLS---------LRKSAPK------------FLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSA 128

  Fly   341 NRLNQNPKKHQNY-GDLLRGEQDTMNILLHFPLTNAQDANFHHDKIDEANVRLMLLYSSSLATNF 404
            :......::.:|: .||.:...|..:|::.|       .|..|..:||                .
  Fly   129 DLEEDEGEQQKNFITDLDKRAIDESDIIMTF-------LNKRHHNVDE----------------L 170

  Fly   405 RRGPGSRKNKISQISGNDNIERHCNFGDVNLNQSNKNSSQQLTLKVYQ------LLSANRRRKIT 463
            |...|.|.                 :.||: |..|.|......|::||      .|:|||...||
  Fly   171 RHEHGRRL-----------------WFDVS-NVPNDNYLVMAELRIYQNANEGKWLTANREFTIT 217

  Fly   464 SRKIEFGNVGFQETR------------TQWIEFDVTKAVRSWLNKSHENLGIEIQCDKCKSIGAR 516
            ...|..|.:| |.|.            ..|:|.:||:.:..||.||.:|.||        .|||.
  Fly   218 VYAIGTGTLG-QHTMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGI--------YIGAH 273

  Fly   517 ILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIMLTNNRSDQYV------ 575
            .:     :.|.|.....|        :.:|       .:..|.:....|:...|..:.:
  Fly   274 AV-----NRPDREVKLDD--------IGLI-------HRKVDDEFQPFMIGFFRGPELIKATAHS 318

  Fly   576 -HHRS----NHDSTWRKDKWTNNCYKLH----QRCCRNQ-LDVAFKSIKGFEFILQPKVFDAGYC 630
             ||||    :|....:|....||...|.    .|.|:.| |.:.||.:...::|:.|:.:.|.||
  Fly   319 SHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYC 383

  Fly   631 HGRCP---PRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEIL-HV-DENHSDKLKISTW 690
            .|.|.   ..|..|.:||::|:|:...:.|:.|:|||.|::|..|.:| |: |||    :.:..:
  Fly   384 SGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDEN----VNLKKY 444

  Fly   691 SDMQVVECAC 700
            .:|.|..|.|
  Fly   445 RNMIVKSCGC 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	30/97 (31%)
		TGF_beta_maverick	598..700	CDD:381633	35/111 (32%)
gbb	NP_477340.1	TGFb_propeptide	45..305	CDD:459906	71/354 (20%)
		TGF_beta_BMP5_like	353..455	CDD:381639	35/106 (33%)