Protein Alignment mav and INHA

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_002182.1
• Gene: INHA / 3623
• HGNCID: 6065
• Length: 366
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 90/444 - (20%)
• Similarity: 145/444 - (32%)
• Gaps: 140/444 - (31%)

  Fly   313 LHFLSITTNGFNDISNKRLRHRRSLKKINRL-------------------NQNPKKHQNYGDLLR 358
            |.||.:|..|.:......|.....|.|:..|                   .:.|::|...|...|
Human     6 LLFLLLTPQGGHSCQGLELARELVLAKVRALFLDALGPPAVTREGGDPGVRRLPRRHALGGFTHR 70

  Fly   359 G-----EQDTMNILLHFPLTNA--QDANFHHDKIDEANVRLM-LLYSSSLATNFRRGPGSRKNKI 415
            |     |:|....:| ||.|:|  :|.:.......||...|. .::..|..|.      ||:...
Human    71 GSEPEEEEDVSQAIL-FPATDASCEDKSAARGLAQEAEEGLFRYMFRPSQHTR------SRQVTS 128

  Fly   416 SQISGNDNIERHCNFGDVNLNQSNKNSSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRTQ 480
            :|:..:..::|.        ..:..|||:.|    ..||:.:....: :..:..|:     ....
Human   129 AQLWFHTGLDRQ--------GTAASNSSEPL----LGLLALSPGGPV-AVPMSLGH-----APPH 175

  Fly   481 WIEFDVTKAVRSWLNKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNI 545
            |....:..:..|.|  :|..|.:.::|..|           :.|..|.:|          |.|
Human   176 WAVLHLATSALSLL--THPVLVLLLRCPLC-----------TCSARPEAT----------PFL-- 215

  Fly   546 IGHGTLNSQQHGDADIHQIMLTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKL----------HQR 600
            :.|........|:.                ..||....:|   .|:.:..:|          |..
Human   216 VAHTRTRPPSGGER----------------ARRSTPLMSW---PWSPSALRLLQRPPEEPAAHAN 261

  Fly   601 CCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRC----PPR---------HNPAHHHALLQSLIW 652
            |.|..|:::|:.:....:|:.|..|...||||.|    ||.         ..||..::||.
Human   262 CHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLLP---- 322

  Fly   653 QEDHKRAPRPCCT--PSKLEMLEILHV----DENHSDKLKISTWSDMQVVECAC 700
                  ..:|||.  |..:..   |||    |..:|  .|..|..::....|||
Human   323 ------GAQPCCAALPGTMRP---LHVRTTSDGGYS--FKYETVPNLLTQHCAC 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	11/63 (17%)
		TGF_beta	599..700	CDD:278448	30/119 (25%)
INHA	NP_002182.1	TGFB	262..366	CDD:214556	32/119 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810