Protein Alignment mav and tgfb1a

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_878293.1
• Gene: tgfb1a / 359834
• ZFINID: ZDB-GENE-030618-1
• Length: 377
• Species: Danio rerio
• Alignment Length: 378
• Identity: 92/378 - (24%)
• Similarity: 156/378 - (41%)
• Gaps: 100/378 - (26%)

  Fly   371 PLTNAQDANFHHDKIDEANVRLMLLYSSSLATNFRRGPGSRKNKISQISGNDNIERHCNFG-DVN 434
            |.:.|.|..   .||.::   |:.||:|::..:     ...|.||..:...|  |.:  || :|:
Zfish    53 PESGADDDG---QKIPDS---LLSLYNSTVELS-----EEMKTKIVPVQDED--EDY--FGKEVH 102

  Fly   435 ---LNQSNKNSSQQLTLKV---------YQLLS-ANRRRKITS------RKIE-FGNVGFQ---- 475
               ..|:..|:..|:...|         |:||| |..|.:|.:      :::| :..||.|
Zfish   103 KFVFQQAQNNTKHQMFFNVSEMKRSIPDYRLLSQAELRLRIKNPTMDQEQRLELYRGVGDQARYL 167

  Fly   476 -------ETRTQWIEFDVTKAVRSWL--NKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTA 531
                   :...:|:.|||.:.:..||  ::..|.|.:.:.|| ||:                :..
Zfish   168 GTRFVSKDLSNRWLSFDVKQTMIEWLQGSEDEETLELRLYCD-CKA----------------NQQ 215

  Fly   532 SSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIML----------TNNRSDQYVHHRS--NHDST 584
            |:|:.|     ..|.|   |:.|:...|.:..:|:          :|..|...|..|.  ..|.|
Zfish   216 STDKFL-----FTISG---LDKQRGDTAGLADMMVKPYILALSLPSNGNSLASVRKRRAVGTDET 272

  Fly   585 WRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCPPRHNPAHHHALLQS 649
                     |.:..:.||..:|.:.|:...|:::|.:||.:.|.||.|.|....|..:.::.:.:
Zfish   273 ---------CDEKTETCCMRKLYIDFRKDLGWKWIHKPKGYFANYCMGSCTYIWNAENKYSQILA 328

  Fly   650 LIWQEDHKRAPRPCCTPSKLEMLEIL-HVDENHSDKLKISTWSDMQVVECACS 701
            |....:...:.:|||.|:.|:.|.|| :|...|    |:...|:|.|..|.||
Zfish   329 LYKHHNPGASAQPCCVPAILDPLPILYYVGRQH----KVEQLSNMVVRNCKCS 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	21/93 (23%)
		TGF_beta	599..700	CDD:278448	30/101 (30%)
tgfb1a	NP_878293.1	TGFb_propeptide	20..248	CDD:366248	53/234 (23%)
		TGF_beta_TGFB1	280..377	CDD:381654	30/100 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1343
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810