Protein Alignment mav and dpp

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 695
• Identity: 143/695 - (20%)
• Similarity: 250/695 - (35%)
• Gaps: 199/695 - (28%)

  Fly    96 KIWFILILLMSTQHQV-----------------------------SGHGIFRQ------TSSSKA 125
            :.|.:|:.:::|...:                             ||.|..|.      .|:|.|
  Fly     2 RAWLLLLAVLATFQTIVRVASTEDISQRFIAAIAPVAAHIPLASASGSGSGRSGSRSVGASTSTA 66

  Fly   126 VFSYYQP-KENITFTNLQLQNLENEAKRLETNQHPIIRAKSTPKMGLKNVFESFSKQSRDSIYNA 189
            :...:.| .|..:|::      .:::.|.:||:.|       .|......|....|...|.:.|
  Fly    67 LAKAFNPFSEPASFSD------SDKSHRSKTNKKP-------SKSDANRQFNEVHKPRTDQLEN- 117

  Fly   190 SSNKYSLINVSQSKNFPQLFNKKLSVQWINTVPIQSRQTRETRDIGLETKRHSKPSKRVDETRLK 254
            |.||        ||   ||.||                           ..|:|.:  |.|.|..
  Fly   118 SKNK--------SK---QLVNK---------------------------PNHNKMA--VKEQRSH 142

  Fly   255 HLVLKGLGIKKLPDMRKVNISQAEYSSKYIEYLSRLRSNQEKG-NSYFNNFMGASFTRDLHFLSI 318
            |        ||....|.....||..|::         |:|... .|.|.........|::..:::
  Fly   143 H--------KKSHHHRSHQPKQASASTE---------SHQSSSIESIFVEEPTLVLDREVASINV 190

  Fly   319 TTN--------GFNDISNKRL-------------RHRRSLKKINRLNQNPKKHQN---------- 352
            ..|        |.:..|.:.|             ...:||..:..:.:.||..::
  Fly   191 PANAKAIIAEQGPSTYSKEALIKDKLKPDPSTLVEIEKSLLSLFNMKRPPKIDRSKIIIPEPMKK 255

  Fly   353 -YGDLLRGEQDTMNILLHFPLTNAQDA--NFHH--DKIDEANVRLMLLYSSSLATNFRRGPGSRK 412
             |.:::..|.|::||.....||.:.:.  :|.|  .|||:   |....:...|..:.:..|...|
  Fly   256 LYAEIMGHELDSVNIPKPGLLTKSANTVRSFTHKDSKIDD---RFPHHHRFRLHFDVKSIPADEK 317

  Fly   413 NKISQISGNDNIERHCNFGDVNLNQSNKNSSQQLTLKVYQL--LSANRRRKITSRKIEFGNVGFQ 475
            .|.:::    .:.|......|..::|:.|.::...| ||.:  :....:|:.:...::...|...
  Fly   318 LKAAEL----QLTRDALSQQVVASRSSANRTRYQVL-VYDITRVGVRGQREPSYLLLDTKTVRLN 377

  Fly   476 ETRTQWIEFDVTKAVRSWLNKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDE-H--- 536
            .|.|  :..||..||..||.....|.|:.::....:|:..      :|....|...|:|| |
  Fly   378 STDT--VSLDVQPAVDRWLASPQRNYGLLVEVRTVRSLKP------APHHHVRLRRSADEAHERW 434

  Fly   537 LNLMPVLNIIGHGTLNSQQHGDADIHQIM--------LTNNRSDQYVHHRSNHDSTWRKDKWTNN 593
            .:..|:|    ....:..:|....|..:.        ..|.|..:....|.|||.|
  Fly   435 QHKQPLL----FTYTDDGRHKARSIRDVSGGEGGGKGGRNKRQPRRPTRRKNHDDT--------- 486

  Fly   594 CYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCP---PRHNPAHHHALLQSLIWQED 655
                   |.|:.|.|.|..:...::|:.|..:||.||||:||   ..|..:.:||::|:|:...:
  Fly   487 -------CRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMN 544

  Fly   656 HKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
            ..:.|:.||.|::|:.:.:|::::..:..||  .:.:|.||.|.|
  Fly   545 PGKVPKACCVPTQLDSVAMLYLNDQSTVVLK--NYQEMTVVGCGC 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	15/65 (23%)
		TGF_beta	599..700	CDD:278448	32/103 (31%)
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	49/238 (21%)
		TGFB	487..588	CDD:214556	33/103 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466516
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840