Protein Alignment mav and Inhba

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_058824.1
• Gene: Inhba / 29200
• RGDID: 62074
• Length: 424
• Species: Rattus norvegicus
• Alignment Length: 483
• Identity: 94/483 - (19%)
• Similarity: 170/483 - (35%)
• Gaps: 129/483 - (26%)

  Fly   241 HSKPSKRVDETRLKHLVLKGLGIKKLPDMRKVNISQAEYSSKYIEYLSRLRSNQEKGNSYFNNFM 305
            :|:|  .:.|...|| :|..|.:||.||     ::|....:..:..:
  Rat    49 NSQP--EMVEAVKKH-ILNMLHLKKRPD-----VTQPVPKAALLNAI------------------ 87

  Fly   306 GASFTRDLHFLSITTNGFNDISNKRLRHRRSLKKINRLNQNPKKHQNYGDLLRGEQDTMNILLHF 370
                 |.||...:..||:.:|.:...|         |...|....|....:...|..|....|||
  Rat    88 -----RKLHVGKVGENGYVEIEDDIGR---------RAEMNELMEQTSEIITFAESGTARKTLHF 138

  Fly   371 PLT-NAQDANFHHDKIDEANVRLMLLYSSSLATNFRRGPGSRKNKISQISGNDNIERHCNFGDVN 434
            .:: ...|.:.    ::.|.|.|.|....:..|         :.|::                :.
  Rat   139 EISKEGSDLSV----VERAEVWLFLKVPKANRT---------RTKVT----------------IR 174

  Fly   435 LNQSNKNSSQQLTL--KVYQL-LSANRRRKITSRKIEFGNVGFQETRTQWIEFDVTKAVRSWLNK 496
            |.|..|:....|.:  :..:: |...|...:.|.|:      ....::.|..|.|:.:::..|::
  Rat   175 LFQQQKHPQGSLDMGDEAEEMGLKGERSELLLSEKV------VDARKSTWHIFPVSSSIQRLLDQ 233

  Fly   497 SHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQHGDADI 561
            ...:|.:.|.|::|:..||.::.                 |.......:.|.|  ..:...|..:
  Rat   234 GKSSLDVRIACEQCQESGASLVL-----------------LGKKKKKEVDGDG--KKKDGSDGGL 279

  Fly   562 HQIMLTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFD 626
            .:....::|....:..|.:.|...|:.:....|......||:.|..|:||.|...::|:.|..:.
  Rat   280 EEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYH 344

  Fly   627 AGYCHGRCPPR-----------HNPAHHHALLQSLIWQEDHKRAP----RPCCTPSKLEMLEILH 676
            |.||.|.||..           |:...:|..::.        .:|    :.||.|:||..:.:|:
  Rat   345 ANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRG--------HSPFANLKSCCVPTKLRPMSMLY 401

  Fly   677 VDENHSDKLKISTWSDMQ---VVECACS 701
            .|:..:...|     |:|   |.||.||
  Rat   402 YDDGQNIIKK-----DIQNMIVEECGCS 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	16/82 (20%)
		TGF_beta_maverick	598..700	CDD:381633	31/119 (26%)
Inhba	NP_058824.1	TGFb_propeptide	56..291	CDD:480997	55/326 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..306		7/43 (16%)
		TGF_beta_INHBA	317..424	CDD:381674	31/119 (26%)