Protein Alignment mav and BMP10

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_055297.1
• Gene: BMP10 / 27302
• HGNCID: 20869
• Length: 424
• Species: Homo sapiens
• Alignment Length: 431
• Identity: 108/431 - (25%)
• Similarity: 171/431 - (39%)
• Gaps: 101/431 - (23%)

  Fly   340 INRLNQNPKKHQN--YGDLLRGEQD--TMNILLH------FPLTNAQDANFHHDKIDEANV---R 391
            |..|.|:|.:...  :||:. .|||  ..|.||.      ....|..|....    |.|.|   .
Human    24 IMNLEQSPLEEDMSLFGDVF-SEQDGVDFNTLLQSMKDEFLKTLNLSDIPTQ----DSAKVDPPE 83

  Fly   392 LMLLYSSSLATNFRRGPGSRKNKISQISGNDNIERHCNFGDV-------NLNQSNKNSSQQLTLK 449
            .||...:..||:....|.:  |.|......|...:..:|..:       |::..:........|:
Human    84 YMLELYNKFATDRTSMPSA--NIIRSFKNEDLFSQPVSFNGLRKYPLLFNVSIPHHEEVIMAELR 146

  Fly   450 VYQLLSANRR------RKITSRKI---EFGNVGFQE-----------TRTQWIEFDVTKAVRSWL 494
            :|.|:..:|.      ||||..::   :..|.|.:.           |.::|..||||.|:|.|.
Human   147 LYTLVQRDRMIYDGVDRKITIFEVLESKGDNEGERNMLVLVSGEIYGTNSEWETFDVTDAIRRWQ 211

  Fly   495 ---NKSHE-NLGIEIQCDKCKSIGA-RILSDFSP-----------STPPRSTASSDEHLNLM--- 540
               :.:|: .:.||.:.|:.:...: |:..|.|.           |....|.....|.||.|
Human   212 KSGSSTHQLEVHIESKHDEAEDASSGRLEIDTSAQNKHNPLLIVFSDDQSSDKERKEELNEMISH 276

  Fly   541 ---PVLNIIGHGTLNSQQHGDADIHQIMLTNNRSDQYVHHRSN--HDSTWRKDKWTNNCYKLHQR 600
               |.|:.:|   |:|...|..:           :..:..|||  :|||.|..:.....|
Human   277 EQLPELDNLG---LDSFSSGPGE-----------EALLQMRSNIIYDSTARIRRNAKGNY----- 322

  Fly   601 CCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCPPRHNPAHH-----HALLQSLIWQEDHKRAP 660
            |.|..|.:.||.|....:|:.|..::|..|.|.|  .:..|.|     ||::|:|:..::.::|.
Human   323 CKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVC--NYPLAEHLTPTKHAIIQALVHLKNSQKAS 385

  Fly   661 RPCCTPSKLEMLEILHVDEN-HSDKLKISTWSDMQVVECAC 700
            :.||.|:|||.:.||::|:. .:.|.|   :..|.|.||.|
Human   386 KACCVPTKLEPISILYLDKGVVTYKFK---YEGMAVSECGC 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	22/87 (25%)
		TGF_beta	599..700	CDD:278448	34/106 (32%)
BMP10	NP_055297.1	TGFb_propeptide	55..256	CDD:279078	42/206 (20%)
		TGF_beta	321..423	CDD:278448	35/111 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810