Protein Alignment mav and GDF9

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_005251.1
• Gene: GDF9 / 2661
• HGNCID: 4224
• Length: 454
• Species: Homo sapiens
• Alignment Length: 456
• Identity: 89/456 - (19%)
• Similarity: 156/456 - (34%)
• Gaps: 150/456 - (32%)

  Fly   310 TRDLHFLS------ITTNGFNDISNKRLRHR-RSLKKINRLNQNPKKHQNYGDLLRGEQDTMNIL 367
            :|.||::.      .|..|....:...|.:. |......|..|.|      ||.:.|...::.:|
Human    83 SRALHYMKKLYKTYATKEGIPKSNRSHLYNTVRLFTPCTRHKQAP------GDQVTGILPSVELL 141

  Fly   368 LHFPLTNAQDANFHHDKID--EANVRLMLLYSSSLATNFRRGPGSRKNKISQISGNDNIERHCNF 430
                        |:.|:|.  |..::.:|||                |..:.:|.:..::..||.
Human   142 ------------FNLDRITTVEHLLKSVLLY----------------NINNSVSFSSAVKCVCNL 178

  Fly   431 GDVNLNQSNKNSSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRTQWIEFDVTKAVRSWL- 494
                :.:..|:||:.|....|..        ..:.:.|||.      :.:||:.|||..::..:
Human   179 ----MIKEPKSSSRTLGRAPYSF--------TFNSQFEFGK------KHKWIQIDVTSLLQPLVA 225

  Fly   495 -NKSHENLGIEIQC--DKCKSIGAR---------------ILSDFS---------------PSTP 526
             ||...::.|...|  |:.:...|:               .|:|.|               ||..
Human   226 SNKRSIHMSINFTCMKDQLEHPSAQNGLFNMTLVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQG 290

  Fly   527 PRSTASSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIMLTNNRSDQYVHHRS------------ 579
            |    ..:..|:..||              |:.     ...:.||..:.|.|.
Human   291 P----DQERSLSAYPV--------------GEE-----AAEDGRSSHHRHRRGQETVSSELKKPL 332

  Fly   580 -----NHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCPPRHN 639
                 |....:|:.....|..:||      ...::|..:|...:|:.|..::..||.|.||  ..
Human   333 GPASFNLSEYFRQFLLPQNECELH------DFRLSFSQLKWDNWIVAPHRYNPRYCKGDCP--RA 389

  Fly   640 PAHH-----HALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECA 699
            ..|.     |.::|::|:::.....|||.|.|:|...|.:|.::.:.|  :....:.||...:|.
Human   390 VGHRYGSPVHTMVQNIIYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGS--IAYKEYEDMIATKCT 452

  Fly   700 C 700
            |
Human   453 C 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	15/65 (23%)
		TGF_beta	599..700	CDD:278448	25/105 (24%)
GDF9	NP_005251.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..330		5/31 (16%)
		TGF_beta	353..453	CDD:306518	27/109 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810