DRSC/TRiP Functional Genomics Resources

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Protein Alignment mav and Bmp4

DIOPT Version :9

Sequence 1:NP_524626.1 Gene:mav / 43804 FlyBaseID:FBgn0039914 Length:701 Species:Drosophila melanogaster
Sequence 2:NP_036959.2 Gene:Bmp4 / 25296 RGDID:2213 Length:408 Species:Rattus norvegicus


Alignment Length:398 Identity:90/398 - (22%)
Similarity:149/398 - (37%) Gaps:97/398 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   342 RLNQNPKKHQNYGDLLRG-----------EQDTMNILLHFPLTNAQDAN----FHHDK------- 384
            |....|.|.....|.:|.           |:.:....|.:|...|..||    |||::       
  Rat    68 RRRPQPSKSAVIPDYMRDLYRLQSGEEEEEEQSQGTGLEYPERPASRANTVRSFHHEEHLENIPG 132

  Fly   385 IDEANVRLMLLYSSSLATN----------FRRGPGSRKNKISQISGNDNIERHCNFGDVNLNQSN 439
            ..|::........||:..|          ||          .|:....:.|:  .|..:|:.:..
  Rat   133 TSESSAFRFFFNLSSIPENEVISSAELRLFR----------EQVDQGPDWEQ--GFHRINIYEVM 185

  Fly   440 KNSSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRTQWIEFDVTKAVRSWLNKSHENLGIE 504
            |..:        :::..:...::...::...||      |:|..|||:.||..|..:...|.|:.
  Rat   186 KPPA--------EMVPGHLITRLLDTRLVHHNV------TRWETFDVSPAVLRWTREKQPNYGLA 236

  Fly   505 IQCDKCKSI----GARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIM 565
            |:.......    |..:  ..|.|.|    ..|.....|.|:|...||         |...|  .
  Rat   237 IEVTHLHQTRTHQGQHV--RISRSLP----QGSGNWAQLRPLLVTFGH---------DGRGH--T 284

  Fly   566 LTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYC 630
            ||..|:.:...|   |....||.         ::.|.|:.|.|.|..:...::|:.|..:.|.||
  Rat   285 LTRRRAKRSPKH---HPQRSRKK---------NKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYC 337

  Fly   631 HGRCP---PRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSD 692
            ||.||   ..|..:.:||::|:|: ...:...|:.||.|::|..:.:|::||  .||:.:..:.:
  Rat   338 HGDCPFPLADHLNSTNHAIVQTLV-NSVNSSIPKACCVPTELSAISMLYLDE--YDKVVLKNYQE 399

  Fly   693 MQVVECAC 700
            |.|..|.|
  Rat   400 MVVEGCGC 407

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mavNP_524626.1 TGFb_propeptide <442..506 CDD:279078 12/63 (19%)
TGF_beta 599..700 CDD:278448 32/103 (31%)
Bmp4NP_036959.2 TGFb_propeptide 41..276 CDD:395559 46/239 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 91..113 3/21 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 281..307 8/39 (21%)
TGF_beta_BMP4_BMP2B 302..408 CDD:381661 35/118 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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