Protein Alignment mav and Gdf6

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001013056.1
• Gene: Gdf6 / 252834
• RGDID: 620104
• Length: 452
• Species: Rattus norvegicus
• Alignment Length: 584
• Identity: 124/584 - (21%)
• Similarity: 196/584 - (33%)
• Gaps: 184/584 - (31%)

  Fly   166 TPKMGLKNVFESFSKQSRDSIYNASSNKYSLINVSQSKNFPQLFNKKLSVQWINTVPIQSRQTRE 230
            ||::.|..:|.............||.:..|...:..:|:.......|:     ...|.:|.:.|
  Rat     3 TPRVLLWAIFLISFLWDLPGFQQASISSSSSTELDSTKDVENRKGGKM-----QRTPQESAEGR- 61

  Fly   231 TRDIGLETKRHSKPSKRVDETRLKHLVLKGLGIKKLPDMRKVNISQAEYS-SKYIEYLSRLRSNQ 294
                   |.:..:|  |.:|.|.:   |.|..:.:.|..|...:...||. |.|..|     |..
  Rat    62 -------TPKEHRP--RPNELRRR---LPGQSLGQEPPGRGPRVVPHEYMLSIYRTY-----SIA 109

  Fly   295 EK---GNSYFNNFMGASFTRDLHFLSITTNGFNDISNKRLRHRRSLKKINRLNQNPKKHQNYGDL 356
            ||   ..|:|.:...|:     ...|....|.:|:|:..||.::.|..::.|:.   |.:..|..
  Rat   110 EKLGINASFFQSSKSAN-----TITSFVDRGLDDLSHTPLRRQKYLFDVSTLSD---KEELVGAE 166

  Fly   357 LR----------GEQDTMNILLHFPLTNAQDANFHHDKIDEANVRLMLLYSSSLATNFRRGPGS- 410
            ||          |.|.....|..||..:.                 :||.|.:|..   :||..
  Rat   167 LRLYRQAPPTPWGPQTRPLHLQLFPCLSP-----------------LLLDSRTLDP---QGPTEA 211

  Fly   411 -----------RKNKISQISGNDNIERHCNFGDVNLNQSNKNSSQQLTLKVYQLLSANRRRKITS 464
                       |.....|:.    :|....:|:::...|                .|..|....|
  Rat   212 GWEVFDVWQVLRPQPWKQLC----LELRAVWGELDARDS----------------GARPRGPQQS 256

  Fly   465 RKIEFGNVGF------QETRTQWIEFDVTKAVRSWL-NKSHENLGIEIQCDKCKSIGARILSDFS 522
            ..::..::||      .:.|...:.|  |::.|..| .:.||.||      ..::.||. .|..:
  Rat   257 PPLDLRSLGFGRRVRPPQERALLVVF--TRSQRKNLFTEMHEQLG------SAEAAGAE-GSWPA 312

  Fly   523 PSTPP-------------RSTASSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIMLTNNRSDQY 574
            ||..|             |.||.|..|                .::||.
  Rat   313 PSGAPDAGSWLPSPGRRRRRTALSSRH----------------GKRHGK---------------- 345

  Fly   575 VHHRSNHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRC--PPR 637
                                 |...||.|..|.|.||.:...::|:.|..::|.:|.|.|  |.|
  Rat   346 ---------------------KSRLRCSRKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLR 389

  Fly   638 -HNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
             |....:||::|:|:...|....|..||.|:||..:.||::|..::...|  .:.||.|..|.|
  Rat   390 SHLEPTNHAIIQTLMNSMDPGSTPPSCCVPTKLTPISILYIDAGNNVVYK--QYEDMVVESCGC 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	14/70 (20%)
		TGF_beta	599..700	CDD:278448	35/103 (34%)
Gdf6	NP_001013056.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..93		15/81 (19%)
		TGFb_propeptide	66..282	CDD:279078	53/273 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	244..267		5/38 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..348		14/100 (14%)
		TGF_beta	350..451	CDD:278448	35/102 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810