Protein Alignment mav and Gdf15

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001317616.1
• Gene: Gdf15 / 23886
• MGIID: 1346047
• Length: 303
• Species: Mus musculus
• Alignment Length: 350
• Identity: 61/350 - (17%)
• Similarity: 122/350 - (34%)
• Gaps: 111/350 - (31%)

  Fly   392 LMLLYS-----SSLATNFRR--GPGSRKNKISQISG--NDNIERHCNFGDVNLNQSNKNSSQQLT 447
            |:||.|     .:||...:|  ||.|:.| ..::.|  .|.:.|      ::.|||.::|:.:
Mouse    25 LLLLLSWPSQGDALAMPEQRPSGPESQLN-ADELRGRFQDLLSR------LHANQSREDSNSE-- 80

  Fly   448 LKVYQLLSANRRRKITSRKIEFGNVG---------------------------FQETRTQWIEFD 485
                  .|.:...:|.|.::..|:.|                           ...|...|   |
Mouse    81 ------PSPDPAVRILSPEVRLGSHGQLLLRVNRASLSQGLPEAYRVHRALLLLTPTARPW---D 136

  Fly   486 VTKAVRSWLNKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGT 550
            :|:.::.         .:.::..:..::..|:       |||...|       ::|
Mouse   137 ITRPLKR---------ALSLRGPRAPALRLRL-------TPPPDLA-------MLP--------- 169

  Fly   551 LNSQQHGDADIH---QIMLTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQRCCR-NQLDVAFK 611
                 .|...:.   ::.....|...:.|.|             ::|.....|||. ..:....:
Mouse   170 -----SGGTQLELRLRVAAGRGRRSAHAHPR-------------DSCPLGPGRCCHLETVQATLE 216

  Fly   612 SIKGFEFILQPKVFDAGYCHGRCPPRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILH 676
            .:...:::|.|:......|.|.||..:..|:.||.:::.:......:.|.|||.||....:.::|
Mouse   217 DLGWSDWVLSPRQLQLSMCVGECPHLYRSANTHAQIKARLHGLQPDKVPAPCCVPSSYTPVVLMH 281

  Fly   677 VDENHSDKLKISTWSDMQVVECACS 701
            ..::   .:.:.|:.|:....|.|:
Mouse   282 RTDS---GVSLQTYDDLVARGCHCA 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	10/90 (11%)
		TGF_beta	599..700	CDD:278448	22/101 (22%)
Gdf15	NP_001317616.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810