Protein Alignment mav and Mstn

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_034964.1
• Gene: Mstn / 17700
• MGIID: 95691
• Length: 376
• Species: Mus musculus
• Alignment Length: 231
• Identity: 55/231 - (23%)
• Similarity: 89/231 - (38%)
• Gaps: 68/231 - (29%)

  Fly   481 WIEFDVTKAVRSWLNKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNI 545
            |...||...:::||.:...||||||          :.|.:.............::.||  |.|.:
Mouse   204 WQSIDVKTVLQNWLKQPESNLGIEI----------KALDENGHDLAVTFPGPGEDGLN--PFLEV 256

  Fly   546 IGHGTLNSQQHGDADIHQIMLTNNRSDQYVHHRSNHDSTWRKDKWTNNC--YKLHQRCCRNQLDV 608
                             ::..|..||              |:| :..:|  :....||||..|.|
Mouse   257 -----------------KVTDTPKRS--------------RRD-FGLDCDEHSTESRCCRYPLTV 289

  Fly   609 AFKSIKGFEFILQPKVFDAGYCHGRC--------PPRHNPAHHHALLQSLIWQEDHKRAPRPCCT 665
            .|::. |:::|:.||.:.|.||.|.|        |..|           |:.|.:.:.:..||||
Mouse   290 DFEAF-GWDWIIAPKRYKANYCSGECEFVFLQKYPHTH-----------LVHQANPRGSAGPCCT 342

  Fly   666 PSKLEMLEILHVDENHSDKLKISTWSDMQVVECACS 701
            |:|:..:.:|:.  |..:::.......|.|..|.||
Mouse   343 PTKMSPINMLYF--NGKEQIIYGKIPAMVVDRCGCS 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	11/36 (31%)
		TGF_beta_maverick	598..700	CDD:381633	31/109 (28%)
Mstn	NP_034964.1	TGFb_propeptide	37..254	CDD:480997	15/61 (25%)
		TGF_beta_GDF8	269..376	CDD:381658	32/120 (27%)