DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mav and Inhbb

DIOPT Version :9

Sequence 1:	NP_524626.1	Gene:	mav / 43804	FlyBaseID:	FBgn0039914	Length:	701	Species:	Drosophila melanogaster
Sequence 2:	NP_032407.1	Gene:	Inhbb / 16324	MGIID:	96571	Length:	411	Species:	Mus musculus

Alignment Length:	294	Identity:	65/294 - (22%)
Similarity:	110/294 - (37%)	Gaps:	79/294 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   436 NQSNKN-----SSQQLTLKVY-QLLSANRRRKITSRKIEFGNVGFQE----------------TR 478
            |:.|:|     :|..|.||:. .:|....|||:..:      |.|||                .|
Mouse   169 NEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVK------VYFQEQGHGDRWNVVEKKVDLKR 227

  Fly   479 TQWIEFDVTKAVRSWLNKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVL 543
            :.|..|.:|:|:::...:....|.:::|||.|                        :.|.::||.
Mouse   228 SGWHTFPITEAIQALFERGERRLNLDVQCDSC------------------------QELAVVPVF 268

  Fly   544 NIIGHGTLNSQQHGDADIHQIMLTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQRCCRNQLDV 608
            ...|     .:.|....:.|..|.::|      ||..        |....|......|||.|..:
Mouse   269 VDPG-----EESHRPFVVVQARLGDSR------HRIR--------KRGLECDGRTSLCCRQQFFI 314

  Fly   609 AFKSIKGFEFILQPKVFDAGYCHGRCP------PRHNPAHHHALLQSLIWQEDHKRAPRPCCTPS 667
            .|:.|...::|:.|..:...||.|.||      |....:.|.|::.....:..:......||.|:
Mouse   315 DFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGPVNSCCIPT 379

  Fly   668 KLEMLEILHVDENHSDKLKISTWSDMQVVECACS 701
            ||..:.:|:.|:.::  :......:|.|.||.|:
Mouse   380 KLSSMSMLYFDDEYN--IVKRDVPNMIVEECGCA 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	18/80 (23%)
mav	NP_524626.1	TGF_beta	599..700	CDD:278448	27/106 (25%)
Inhbb	NP_032407.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	28..69
		TGFb_propeptide	73..282	CDD:307025	30/147 (20%)
		TGFB	307..410	CDD:214556	27/104 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810