Protein Alignment mav and Gdf11

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_034402.1
• Gene: Gdf11 / 14561
• MGIID: 1338027
• Length: 405
• Species: Mus musculus
• Alignment Length: 252
• Identity: 62/252 - (24%)
• Similarity: 94/252 - (37%)
• Gaps: 69/252 - (27%)

  Fly   458 RRRKITSRKIEFGNVGFQETRT-QWIEFDVTKAVRSWLNKSHENLGIEIQCDKCKSIGARILSDF 521
            |..:|.|.|||.      .:|: .|...|..:.:.||..:...|.||||..             |
Mouse   215 RHIRIRSLKIEL------HSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINA-------------F 260

  Fly   522 SPSTPPRSTASSDEHLNLMPVLNIIGHGT---LNSQQHGDADIHQIM----LTNNRSDQYVHHRS 579
            .||                        ||   :.|...|...:|..|    |.|.:       ||
Mouse   261 DPS------------------------GTDLAVTSLGPGAEGLHPFMELRVLENTK-------RS 294

  Fly   580 NHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCPPRHNPAHHH 644
            ..:.....|:     :....||||..|.|.|::. |:::|:.||.:.|.||.|:|.......:.|
Mouse   295 RRNLGLDCDE-----HSSESRCCRYPLTVDFEAF-GWDWIIAPKRYKANYCSGQCEYMFMQKYPH 353

  Fly   645 ALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECACS 701
            .   .|:.|.:.:.:..|||||:|:..:.:|:.  |...::.......|.|..|.||
Mouse   354 T---HLVQQANPRGSAGPCCTPTKMSPINMLYF--NDKQQIIYGKIPGMVVDRCGCS 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	16/60 (27%)
		TGF_beta_maverick	598..700	CDD:381633	30/101 (30%)
Gdf11	NP_034402.1	TGFb_propeptide	59..283	CDD:480997	24/110 (22%)
		TGF_beta_GDF8	299..405	CDD:381658	31/116 (27%)