Protein Alignment mav and Gdf10

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_665684.2
• Gene: Gdf10 / 14560
• MGIID: 95684
• Length: 476
• Species: Mus musculus
• Alignment Length: 221
• Identity: 62/221 - (28%)
• Similarity: 89/221 - (40%)
• Gaps: 54/221 - (24%)

  Fly   520 DFSPSTPPRSTA----------SSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIMLTNNRSDQY 574
            ||.|...|.|:|          |.....|.:|.|:......|::|....   |:...:..|:
Mouse   269 DFEPGAAPNSSADPRVRRAAQVSKPLQDNELPGLDERPAPALHAQNFHK---HEFWSSPFRA--- 327

  Fly   575 VHHRSNHDSTWRKDKWT-------------NNCYKLHQR-------CCRNQLDVAFKSIKGFEFI 619
            :..|:......:||:.|             ....|..:|       |.|..|.|.|..|...|:|
Mouse   328 LKPRTGRKDRKKKDQDTFTAASSQVLDFDEKTMQKARRRQWDEPRVCSRRYLKVDFADIGWNEWI 392

  Fly   620 LQPKVFDAGYCHGRCP---PRHNPAHHHALLQSLIWQEDHKRA-------PRPCCTPSKLEMLEI 674
            :.||.|||.||.|.|.   |:.....:||.:||::      ||       |.|||.|.|:..|.:
Mouse   393 ISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIV------RAVGIVPGIPEPCCVPDKMNSLGV 451

  Fly   675 LHVDENHSDKLKISTWSDMQVVECAC 700
            |.:|||.:..||:  :.:|.|..|||
Mouse   452 LFLDENRNAVLKV--YPNMSVETCAC 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997
		TGF_beta_maverick	598..700	CDD:381633	41/118 (35%)
Gdf10	NP_665684.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..63
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	268..301		8/31 (26%)
		TGF_beta_GDF10	365..476	CDD:381664	43/119 (36%)