DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment mav and Gdf1

DIOPT Version :9

Sequence 1:NP_524626.1 Gene:mav / 43804 FlyBaseID:FBgn0039914 Length:701 Species:Drosophila melanogaster
Sequence 2:NP_001156754.1 Gene:Gdf1 / 14559 MGIID:95683 Length:357 Species:Mus musculus


Alignment Length:112 Identity:35/112 - (31%)
Similarity:56/112 - (50%) Gaps:18/112 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   601 CCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCP-------PRHNPAHHHALLQSLIWQEDHKR 658
            |...:|.|:|:.:....:::.|:.|.|.:|.|.|.       |...||.:||:|::|:    |..
Mouse   251 CRTRRLHVSFREVGWHRWVIAPRGFLANFCQGTCALPETLRGPGGPPALNHAVLRALM----HAA 311

  Fly   659 AP-----RPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
            ||     .|||.|.:|..:.:|..|  :||.:.:..:.||.|.||.|
Mouse   312 APTPGAGSPCCVPERLSPISVLFFD--NSDNVVLRHYEDMVVDECGC 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mavNP_524626.1 TGFb_propeptide <442..506 CDD:279078
TGF_beta 599..700 CDD:278448 34/110 (31%)
Gdf1NP_001156754.1 TGFb_propeptide 36..>141 CDD:279078
TGFB 251..357 CDD:214556 35/112 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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