Protein Alignment mav and Gdf2

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_062379.3
• Gene: Gdf2 / 12165
• MGIID: 1321394
• Length: 428
• Species: Mus musculus
• Alignment Length: 358
• Identity: 81/358 - (22%)
• Similarity: 139/358 - (38%)
• Gaps: 84/358 - (23%)

  Fly   397 SSSLATNFRRGPGSRKNKISQISGND------------NIERHCNFGDVNLN-----QSNKNSSQ 444
            ||:.|:|..|. .|.::.||..:..|            :|.||.......|.     |::.:|:.
Mouse   100 SSTPASNIVRS-FSVEDAISTAATEDFPFQKHILIFNISIPRHEQITRAELRLYVSCQNDVDSTH 163

  Fly   445 QL--TLKVYQLLSANRR-RKITSRKIEFGNVGFQETRTQ-WIEFDVTKAVRSWL------NKSHE 499
            .|  ::.||.:|..:.. .:.|..|....:   |:.|.: |...:|:.||:.|:      ||:..
Mouse   164 GLEGSMVVYDVLEDSETWDQATGTKTFLVS---QDIRDEGWETLEVSSAVKRWVRADSTTNKNKL 225

  Fly   500 NLGIEIQCDKCKSI------GARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQHGD 558
            .:.::...:.|.::      |::.|..|...:..||..:.:..|.|.   .:|||.
Mouse   226 EVTVQSHRESCDTLDISVPPGSKNLPFFVVFSNDRSNGTKETRLELK---EMIGHE--------- 278

  Fly   559 ADIHQIMLTNNRSDQY-VHHRSNHDS-----------TWRKDKWTNNCYKLHQRCCRNQLDVAFK 611
               .:.||.....:.| |...|..:.           ..|:.:.|.    ....|.:..|.|.|:
Mouse   279 ---QETMLVKTAKNAYQVAGESQEEEGLDGYTAVGPLLARRKRSTG----ASSHCQKTSLRVNFE 336

  Fly   612 SIKGFEFILQPKVFDAGYCHGRC---------PPRHNPAHHHALLQSLIWQEDHKRAPRPCCTPS 667
            .|....:|:.||.:||..|.|.|         |.:      ||::|:|:..:...:..:.||.|:
Mouse   337 DIGWDSWIIAPKEYDAYECKGGCFFPLADDVTPTK------HAIVQTLVHLKFPTKVGKACCVPT 395

  Fly   668 KLEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
            ||..:.||:.|:.....||.. :..|.|.||.|
Mouse   396 KLSPISILYKDDMGVPTLKYH-YEGMSVAECGC 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	16/73 (22%)
		TGF_beta	599..700	CDD:278448	32/109 (29%)
Gdf2	NP_062379.3	TGFb_propeptide	75..256	CDD:279078	34/159 (21%)
		TGF_beta	325..427	CDD:278448	32/108 (30%)
		Interaction with ENG. /evidence=ECO:0000250|UniProtKB:Q9UK05	401..415		4/13 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810