Protein Alignment mav and Bmp4

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001303289.1
• Gene: Bmp4 / 12159
• MGIID: 88180
• Length: 408
• Species: Mus musculus
• Alignment Length: 398
• Identity: 91/398 - (22%)
• Similarity: 151/398 - (37%)
• Gaps: 97/398 - (24%)

  Fly   342 RLNQNPKKHQNYGDLLRG-----------EQDTMNILLHFPLTNAQDAN----FHHDK------- 384
            |....|.|.....|.:|.           |:.:....|.:|...|..||    |||::
Mouse    68 RRRPQPSKSAVIPDYMRDLYRLQSGEEEEEEQSQGTGLEYPERPASRANTVRSFHHEEHLENIPG 132

  Fly   385 IDEANVRLMLLYSSSLATN----------FRRGPGSRKNKISQISGNDNIERHCNFGDVNLNQSN 439
            ..|::....|...||:..|          ||          .|:....:.|:  .|..:|:.:..
Mouse   133 TSESSAFRFLFNLSSIPENEVISSAELRLFR----------EQVDQGPDWEQ--GFHRINIYEVM 185

  Fly   440 KNSSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRTQWIEFDVTKAVRSWLNKSHENLGIE 504
            |..:        :::..:...::...::...||      |:|..|||:.||..|..:...|.|:.
Mouse   186 KPPA--------EMVPGHLITRLLDTRLVHHNV------TRWETFDVSPAVLRWTREKQPNYGLA 236

  Fly   505 IQCDKCKSI----GARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIM 565
            |:.......    |..:  ..|.|.|    ..|.:...|.|:|...||         |...|  .
Mouse   237 IEVTHLHQTRTHQGQHV--RISRSLP----QGSGDWAQLRPLLVTFGH---------DGRGH--T 284

  Fly   566 LTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYC 630
            ||..|:.:...|   |....||.         ::.|.|:.|.|.|..:...::|:.|..:.|.||
Mouse   285 LTRRRAKRSPKH---HPQRSRKK---------NKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYC 337

  Fly   631 HGRCP---PRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSD 692
            ||.||   ..|..:.:||::|:|: ...:...|:.||.|::|..:.:|::||  .||:.:..:.:
Mouse   338 HGDCPFPLADHLNSTNHAIVQTLV-NSVNSSIPKACCVPTELSAISMLYLDE--YDKVVLKNYQE 399

  Fly   693 MQVVECAC 700
            |.|..|.|
Mouse   400 MVVEGCGC 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	12/63 (19%)
		TGF_beta	599..700	CDD:278448	32/103 (31%)
Bmp4	NP_001303289.1	TGFb_propeptide	41..276	CDD:279078	47/239 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..111		3/19 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..307		8/39 (21%)
		TGFB	308..408	CDD:214556	33/103 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810