Protein Alignment mav and Bmp4

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_031580.2
• Gene: Bmp4 / 12159
• MGIID: 88180
• Length: 408
• Species: Mus musculus
• Alignment Length: 398
• Identity: 91/398 - (22%)
• Similarity: 151/398 - (37%)
• Gaps: 97/398 - (24%)

  Fly   342 RLNQNPKKHQNYGDLLRG-----------EQDTMNILLHFPLTNAQDAN----FHHDK------- 384
            |....|.|.....|.:|.           |:.:....|.:|...|..||    |||::
Mouse    68 RRRPQPSKSAVIPDYMRDLYRLQSGEEEEEEQSQGTGLEYPERPASRANTVRSFHHEEHLENIPG 132

  Fly   385 IDEANVRLMLLYSSSLATN----------FRRGPGSRKNKISQISGNDNIERHCNFGDVNLNQSN 439
            ..|::....|...||:..|          ||          .|:....:.|:  .|..:|:.:..
Mouse   133 TSESSAFRFLFNLSSIPENEVISSAELRLFR----------EQVDQGPDWEQ--GFHRINIYEVM 185

  Fly   440 KNSSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRTQWIEFDVTKAVRSWLNKSHENLGIE 504
            |..:        :::..:...::...::...||      |:|..|||:.||..|..:...|.|:.
Mouse   186 KPPA--------EMVPGHLITRLLDTRLVHHNV------TRWETFDVSPAVLRWTREKQPNYGLA 236

  Fly   505 IQCDKCKSI----GARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIM 565
            |:.......    |..:  ..|.|.|    ..|.:...|.|:|...||         |...|  .
Mouse   237 IEVTHLHQTRTHQGQHV--RISRSLP----QGSGDWAQLRPLLVTFGH---------DGRGH--T 284

  Fly   566 LTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYC 630
            ||..|:.:...|   |....||.         ::.|.|:.|.|.|..:...::|:.|..:.|.||
Mouse   285 LTRRRAKRSPKH---HPQRSRKK---------NKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYC 337

  Fly   631 HGRCP---PRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSD 692
            ||.||   ..|..:.:||::|:|: ...:...|:.||.|::|..:.:|::||  .||:.:..:.:
Mouse   338 HGDCPFPLADHLNSTNHAIVQTLV-NSVNSSIPKACCVPTELSAISMLYLDE--YDKVVLKNYQE 399

  Fly   693 MQVVECAC 700
            |.|..|.|
Mouse   400 MVVEGCGC 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	15/83 (18%)
		TGF_beta_maverick	598..700	CDD:381633	32/104 (31%)
Bmp4	NP_031580.2	TGFb_propeptide	43..276	CDD:459906	47/239 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..111		3/19 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..307		8/39 (21%)
		TGF_beta_BMP4_BMP2B	302..408	CDD:381661	35/118 (30%)