Protein Alignment mav and Bmp2

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_031579.2
• Gene: Bmp2 / 12156
• MGIID: 88177
• Length: 394
• Species: Mus musculus
• Alignment Length: 349
• Identity: 82/349 - (23%)
• Similarity: 136/349 - (38%)
• Gaps: 92/349 - (26%)

  Fly   379 NFHHDKIDE-------ANVRLMLLYSSSLATN----------FRRGPGSRKNKISQISGNDNIER 426
            :|||::..|       ...|......||:.::          ||       .:|.:..||.:.:.
Mouse   110 SFHHEEAVEELPEMSGKTARRFFFNLSSVPSDEFLTSAELQIFR-------EQIQEALGNSSFQH 167

  Fly   427 HCNFGDVNLNQSNKNSSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRTQWIEFDVTKAVR 491
            .     :|:.:..|.::..|...|.:||......:.||               ||..||||.||.
Mouse   168 R-----INIYEIIKPAAANLKFPVTRLLDTRLVNQNTS---------------QWESFDVTPAVM 212

  Fly   492 SWLNKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASS-----DEH--LNLMPVLNIIGHG 549
            .|..:.|.|.|..::....:.         :|....|....|     |||  ..:.|:|...||
Mouse   213 RWTTQGHTNHGFVVEVAHLEE---------NPGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGH- 267

  Fly   550 TLNSQQHGDADIHQIMLTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIK 614
                    |...|.:           |.|....:..::.|      :|...|.|:.|.|.|..:.
Mouse   268 --------DGKGHPL-----------HKREKRQAKHKQRK------RLKSSCKRHPLYVDFSDVG 307

  Fly   615 GFEFILQPKVFDAGYCHGRCP---PRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILH 676
            ..::|:.|..:.|.||||.||   ..|..:.:||::|:|: ...:.:.|:.||.|::|..:.:|:
Mouse   308 WNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLV-NSVNSKIPKACCVPTELSAISMLY 371

  Fly   677 VDENHSDKLKISTWSDMQVVECAC 700
            :|||  :|:.:..:.||.|..|.|
Mouse   372 LDEN--EKVVLKNYQDMVVEGCGC 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	19/79 (24%)
		TGF_beta_maverick	598..700	CDD:381633	33/104 (32%)
Bmp2	NP_031579.2	TGFb_propeptide	45..265	CDD:459906	40/190 (21%)
		TGF_beta_BMP2	292..394	CDD:381660	34/105 (32%)