Protein Alignment mav and gdf15

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: XP_017946434.1
• Gene: gdf15 / 101733328
• XenbaseID: XB-GENE-5714902
• Length: 377
• Species: Xenopus tropicalis
• Alignment Length: 470
• Identity: 90/470 - (19%)
• Similarity: 171/470 - (36%)
• Gaps: 123/470 - (26%)

  Fly   235 GLETKRHSKPSKRVDETRLKHLVLKGLGIKKLPDMR-KVNISQ-AEYSSKYIEYLSRLRSNQEKG 297
            |::.:...:..|::....:|..:|..||:...|.:| |:::.. .:..|.|.|.|:.||.|..|.
 Frog    28 GVQLRPLVEKEKKMQLEAVKKGILDHLGLNSPPVIREKLDLDDIRKMYSLYQEKLTELRGNISKD 92

  Fly   298 NSYFNNFMGASFTRDLHFLSITTNGFNDISNKRLRHRRSLKKINRLNQNPKKHQNYGDLLRGEQD 362
            ...         .|.:|.|:.|           |..:..|.:...:......|:
 Frog    93 GIP---------ERKVHLLTPT-----------LEKKTQLARKYEIQHGSNSHR----------- 126

  Fly   363 TMNILLHFPLTNAQDANFHHD-KIDEANVRLMLLYSSSLATNFRRGPGSRKNKISQISGNDNIER 426
                   :.|..::...||.: .:..|.::|.....|:|     :..||
 Frog   127 -------YNLVFSRTQTFHQELSVMRAELKLCKKILSTL-----QSVGS---------------- 163

  Fly   427 HCNFGDVNLNQSNKNSSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRTQWIEFDVTKAVR 491
                          ||:.|..:.:|:::.:|.|......|:.......:||    :..:|..||:
 Frog   164 --------------NSTAQPMVNIYKVVESNERHGEEEHKLLDSKPLDKET----LMLNVVSAVQ 210

  Fly   492 SWLNKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQH 556
            .|:..|          :||..:...|.:|.:                      .:.:|....:::
 Frog   211 QWVASS----------EKCLRLELVIPTDIA----------------------FVSNGDKQKEKN 243

  Fly   557 GDADIHQIMLTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQ 621
            .|      ::....:.:..|.......:...|:   .|.|..::|||..|.|:||.|...::|:.
 Frog   244 DD------LILEVETQERAHSNIRKSRSLPADE---ECKKSEKKCCRKSLRVSFKEIGWSDWIIV 299

  Fly   622 PKVFDAGYCHGRCPPRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLK 686
            |:.:...:|.|.||..:.||..||.::..:....:...|.|||.|:..|.:.::|.  |...||.
 Frog   300 PEAYTMHFCDGSCPHNYKPASMHAQIKYRMHHISNGATPAPCCVPASYEPMVLMHY--NTEGKLT 362

  Fly   687 ISTWSDMQVVECACS 701
            ::.:.||.|.:|.|:
 Frog   363 LTPFEDMIVRKCHCA 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	13/63 (21%)
		TGF_beta	599..700	CDD:278448	32/100 (32%)
gdf15	XP_017946434.1	TGFb_propeptide	43..240	CDD:366248	50/305 (16%)
		TGF_beta_GDF15	277..377	CDD:381646	32/101 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D338011at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010