Protein Alignment mav and tgfb1

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: XP_002939433.1
• Gene: tgfb1 / 100498430
• XenbaseID: XB-GENE-488111
• Length: 381
• Species: Xenopus tropicalis
• Alignment Length: 394
• Identity: 92/394 - (23%)
• Similarity: 148/394 - (37%)
• Gaps: 98/394 - (24%)

  Fly   355 DLLRGEQDTMNILLHFPLTNAQDANFHHDKIDEANVRL----MLLYSSSLATNFRRGPGS----- 410
            :.:||:     ||....|....|       :|..|:.:    :.||:|:|.....|....
 Frog    39 EAIRGQ-----ILSKLKLDRTPD-------VDSENMTVPSEAISLYNSTLEVIRERAAKEEAPVW 91

  Fly   411 --------------RKNKISQISGNDNIERHCNFGDVNLNQSNKNSSQQLTLKVYQLLSANRRRK 461
                          |...|:::..|:.:... |...|..|...|:......|::|       |:|
 Frog    92 QEHNIQDYYAKQVHRFESINELKENEFLFTF-NASHVRENVGMKSLLHHAELRMY-------RKK 148

  Fly   462 ITSRKIE------FGN----VGFQE-------TRTQWIEFDVTKAVRSWLNKSHENLGIEIQ--C 507
            .|.:.:|      .||    .|:.:       |..:|:.|||||.|..|||.:.||....::  |
 Frog   149 QTDKNVEQRMELYAGNGTDYSGYLDSKFFTAVTDDEWVSFDVTKTVNEWLNHAEENEEFRLKPAC 213

  Fly   508 DKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIMLTN---N 569
             ||             |....|...|.|..:::       .|.|.:....|.....:::|:   .
 Frog   214 -KC-------------SITTHSKVISIEGFSIL-------RGDLMNLGGDDLKKPYLLITSMPAE 257

  Fly   570 RSDQYVHHRSNHDSTWRKDKWTNNCY-KLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGR 633
            |.|...|.|.      ::......|: .....||...|.:.|:...|:::|.:||.::|.||.|.
 Frog   258 RIDTVSHSRR------KRGVGQEYCFGNSGPNCCVKPLYINFRKDLGWKWIHEPKGYEANYCLGN 316

  Fly   634 CPPRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEIL-HVDENHSDKLKISTWSDMQVVE 697
            ||...:....::.:.||..|.:...:..|||.|..||.|.|: :|..|    .|:...|:|.|..
 Frog   317 CPYIWSTDTQYSKVLSLYNQNNPGASISPCCVPDVLEPLPIIYYVGRN----AKVEQLSNMVVRS 377

  Fly   698 CACS 701
            |.||
 Frog   378 CHCS 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	26/98 (27%)
		TGF_beta_maverick	598..700	CDD:381633	32/102 (31%)
tgfb1	XP_002939433.1	TGFb_propeptide	22..250	CDD:480997	52/251 (21%)
		TGF_beta_TGFB1	283..381	CDD:381654	32/101 (32%)