Protein Alignment mav and gdf9

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: XP_002935305.1
• Gene: gdf9 / 100496740
• XenbaseID: XB-GENE-478149
• Length: 421
• Species: Xenopus tropicalis
• Alignment Length: 508
• Identity: 103/508 - (20%)
• Similarity: 178/508 - (35%)
• Gaps: 159/508 - (31%)

  Fly   251 TRLKHLVLKGLGIKKLPDMRKVNISQAEYSSKY--IEYLSRLRSNQEK--GNSYFNNFMGASFTR 311
            |.|..|.:.|.|:              |||..|  :..|.:..|.:.|  .|:...|.:...:.:
 Frog    14 TWLLPLQIGGFGL--------------EYSEDYSLLPPLFKELSERPKWSDNAPGPNMVAIKYMK 64

  Fly   312 DLHFLSITTNGFNDISNKRLRHRRSLKKINRLNQNPKKHQNYGDLLRGEQDTMNILLHFPLTNAQ 376
            .|:.:|.|..||                 .||::||..:              .:.|..|.|..:
 Frog    65 RLYKMSATKEGF-----------------PRLHKNPVYN--------------TVRLFTPRTECK 98

  Fly   377 --------------DANFHHDKID--EANVRLMLLYSSSLATNFRRGPGSRKNKISQISGNDNIE 425
                          |..|..|::.  |..::.:||||                 :|:...:.||.
 Frog    99 PEREREINGGMQSLDLTFSVDRVSAVEQLLQSLLLYS-----------------VSKRFSSSNIT 146

  Fly   426 RHCNFGDVNLNQSNKNSSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRTQWIEFDVTKAV 490
            ..|:                |.:..|:|.|....|...|...:.      ..|.:|:|.|||..:
 Frog   147 CTCS----------------LEILGYELQSTVCPRAPQSFHFQL------RKRQRWVEIDVTSIL 189

  Fly   491 RSWLNKSHEN--LGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNS 553
            :.:::...:|  ||:...|.|...     ..||:.:.|.:.|.|.       |.|.:..:.|.|.
 Frog   190 QPFISNKRQNIHLGLNFTCMKNNK-----HYDFATTGPFKMTRSP-------PSLLLYLNDTSNK 242

  Fly   554 QQHGDADIHQI--------------MLT----NNRSDQYVHHRSNHD-------------STWRK 587
            ..|... :|.|              :|.    |.:..|....|.|||             .|:..
 Frog   243 AYHRRI-MHDIAEQPLYYPVGRIPSILADDEGNLKLQQMSRRRRNHDYEAILEENTTVVPHTFNF 306

  Fly   588 DKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCP----PRH-NPAHHHALL 647
            .::.......|..|..::..::|..:...::||.|..:...||.|.||    .|: :|.  |.::
 Frog   307 SEYLKQFVYSHNECELHRFRLSFSQLNWDKWILAPHRYSPDYCKGVCPRIVGHRYGSPV--HTIV 369

  Fly   648 QSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECAC 700
            |::|:::.....|||.|.||:...:.:|.::.::|  :....:.||...:|.|
 Frog   370 QNIIYEKVDSSIPRPSCVPSEYRPMSVLTIEPDNS--IAYKEYQDMIATKCTC 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	17/81 (21%)
		TGF_beta_maverick	598..700	CDD:381633	27/106 (25%)
gdf9	XP_002935305.1	TGF_beta_GDF9	318..421	CDD:381673	27/107 (25%)