Protein Alignment mav and gdf5

DIOPT Version :9

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: XP_002662587.1
• Gene: gdf5 / 100334210
• ZFINID: ZDB-GENE-990415-39
• Length: 474
• Species: Danio rerio
• Alignment Length: 409
• Identity: 85/409 - (20%)
• Similarity: 150/409 - (36%)
• Gaps: 103/409 - (25%)

  Fly   333 HRRSLKKINRLNQNPKKHQNYGDLLRGEQDTMNILLHFPLTNAQDANFHHDKIDEANVRLMLLYS 397
            |.|....:...|....||.     |....|.| :.|::.||:             .:|...:|:.
Zfish   127 HLRMKSAVKLENSEEPKHP-----LVIPHDYM-LSLYWSLTS-------------GDVNTSVLHE 172

  Fly   398 SSLA---TNF-RRGPGSRKNKISQISGNDNIERHCNFGDVNLNQSNKNSSQQLTLKVYQLLSANR 458
            :.:|   |:| .||...|...:.:       :|:.    .|::...|.......|::.      |
Zfish   173 AGMANTITSFVDRGQDERAPLLRR-------QRYV----FNISSMEKEGLLGAELRIL------R 220

  Fly   459 RRKITSRKIEFGNVGFQETR------------------------TQWIEFDVTKAVRSWLNKSHE 499
            ::.:.|||..|.. |....|                        :.|..||:.|..:::.|.  .
Zfish   221 KKHMDSRKATFSE-GMAVLRLFTCASGKNAAVLLQARPFDSHSASYWEVFDIWKVFKNFRNT--P 282

  Fly   500 NLGIEIQC-DKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIG--------HGTLNSQQ 555
            .|.:|:.. |..:.:..|:|   ..|...|.|...       ....:.|        :..:.::.
Zfish   283 QLCLELDAVDHGRPLDLRLL---GLSRAGRQTKEK-------AFFVVFGRTKKRGLFYNEIKARS 337

  Fly   556 -HGDADIHQIMLTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFI 619
             |.:..:::.:.|..|..:....|........|           |||.|.||.|.||.:...::|
Zfish   338 GHDNKTVYEYLFTQRRMRRAPLPRGKKPIKNPK-----------QRCNRKQLHVNFKEMGWDDWI 391

  Fly   620 LQPKVFDAGYCHGRC--PPR-HNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENH 681
            :.|..::|.:|.|.|  |.| |....:||::|:|:...|.:..|..||.|::|..:.||::|.
Zfish   392 IAPLEYEAFHCDGVCDFPIRSHLEPTNHAIIQTLMNSMDPRSTPPTCCVPTRLSPISILYIDS-- 454

  Fly   682 SDKLKISTWSDMQVVECAC 700
            ::.:....:.||.|..|.|
Zfish   455 ANNVVYKQYEDMVVESCGC 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<442..506	CDD:279078	15/87 (17%)
		TGF_beta	599..700	CDD:278448	35/103 (34%)
gdf5	XP_002662587.1	TGFb_propeptide	138..320	CDD:279078	41/230 (18%)
		TGF_beta	371..473	CDD:278448	35/103 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810