Protein Alignment mav and lefty1

DIOPT Version :10

• Sequence 1: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001123725.1
• Gene: lefty1 / 100170470
• XenbaseID: XB-GENE-6258963
• Length: 365
• Species: Xenopus tropicalis
• Alignment Length: 371
• Identity: 75/371 - (20%)
• Similarity: 143/371 - (38%)
• Gaps: 108/371 - (29%)

  Fly   384 KIDEANVRLMLL-------YSSSLATN---FRRGPGSRKNKISQISGNDNIERHCNFGDVNLNQS 438
            |:::.:|..:|:       |.|.|.|:   .||...|....:..||||.:|.     |::..:.|
 Frog    43 KLEKRDVEKLLIPRHIQAKYMSMLHTHRERKRRSLPSLAGILRGISGNADIA-----GEIVYSDS 102

  Fly   439 NKNS-----------SQQLT---LKVY----QLLSANRRR--------KITSRKIEFGNVGFQET 477
            :|.:           :.::|   ||::    |:::...||        :::...:|....|...|
 Frog   103 SKQTLVFGMESRIPENSEVTMAELKLFKKPPQIMNVPERRFHRPVNNARVSVYYVEMLTDGTNRT 167

  Fly   478 -----------RTQWIEFDVTKAVRSWLNKSHEN-LGIEIQCDKCKSIGAR---ILSDFSPSTPP 527
                       .:.|..||||:||:.|.....:: :.:||:.|     |.|   ..|:.:.....
 Frog   168 SLVDSRLVPIMESGWRSFDVTQAVQYWTRSGGQSPMHLEIRVD-----GERHGSHASEMAKLVRF 227

  Fly   528 RSTASSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIMLTNNRSDQYVHHRSNHDSTWRKDKWTN 592
            .:.::||..|. .|.|.:.   |||..:||.                           |.|...:
 Frog   228 TTQSASDNSLG-KPELVLY---TLNLDEHGA---------------------------RGDCSAS 261

  Fly   593 NCYKLHQRCCRNQLDVAFKSIKGFEF-ILQPKVFDAGYCHGRC-PPRHNPAHHHALLQSLIWQED 655
            ...|.| .|||.:..:.|:.:...:: |::|..::|.:|.|.| .|:...:|:|
 Frog   262 GAQKDH-ICCREEHFINFRELTWTQYWIIEPAGYNAFHCTGSCKQPKFPLSHYH----------- 314

  Fly   656 HKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECACS 701
              ...|.|.......:..:..|.:....:::::.:.:|.|.:|.|:
 Frog   315 --YGQRTCAVVESAPLPVMYLVKKGDYTEIEVAEFPNMIVEKCGCT 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	24/120 (20%)
		TGF_beta_maverick	598..700	CDD:381633	20/103 (19%)
lefty1	NP_001123725.1	TGFb_propeptide	<113..200	CDD:480997	17/86 (20%)
		TGF_beta_LEFTY1_2	269..357	CDD:381636	19/100 (19%)