DRSC/TRiP Functional Genomics Resources

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Protein Alignment Eph and KIN1

DIOPT Version :9

Sequence 1:NP_524625.3 Gene:Eph / 43803 FlyBaseID:FBgn0025936 Length:1096 Species:Drosophila melanogaster
Sequence 2:NP_010407.1 Gene:KIN1 / 851700 SGDID:S000002529 Length:1064 Species:Saccharomyces cerevisiae


Alignment Length:325 Identity:80/325 - (24%)
Similarity:137/325 - (42%) Gaps:67/325 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   663 RSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQ 727
            :.:.|.:|:.||..:.|.|...:.:.|:|....|                               
Yeast    76 QKERQVELEGKSRENAPKPNTTSQSRVSSSQGMP------------------------------- 109

  Fly   728 AIREFAREIDANYITIEAIIGGGEFG-----------DVC--------------RGRLKIPPNFV 767
              ::|.|:...::..:|. :|.|..|           :||              :.::..||...
Yeast   110 --KQFHRKSLGDWEFVET-VGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNE 171

  Fly   768 QDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTF 832
            ||:....|.|:...|...|.  :.|||:.....||::..|..:.|.||...::.||:..|.|..:
Yeast   172 QDVLERQKKLEKEISRDKRT--IREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDY 234

  Fly   833 LRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIENAS 897
            : :..|..:..|.....|||||.:.||...|.|||||...|::::.....||.|||||...::..
Yeast   235 I-IQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRK 298

  Fly   898 DAYTTRGGKIPVRWTAPEAIAFRKFTSAS-DVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKG 961
            ..:|..|.   :.:.|||.:....:|... ||||:||||: |:..|:.|:.:.::..:.:.|::|
Yeast   299 QLHTFCGS---LYFAAPELLKANPYTGPEVDVWSFGVVLF-VLVCGKVPFDDENSSVLHEKIKQG 359

  Fly   962  961
            Yeast   360  359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EphNP_524625.3 EphR_LBD 85..260 CDD:198439
FN3 387..476 CDD:238020
FN3 536..623 CDD:238020
EphA2_TM 644..736 CDD:291255 11/72 (15%)
PTKc_EphR 736..1002 CDD:270629 69/252 (27%)
Pkinase_Tyr 741..999 CDD:285015 69/247 (28%)
SAM_1 1033..1092 CDD:278937
SAM 1039..1092 CDD:197735
KIN1NP_010407.1 STKc_Kin1_2 118..398 CDD:270979 69/250 (28%)
MARK_C_like 890..1062 CDD:213377
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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