DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eph and YDA

DIOPT Version :9

Sequence 1:	NP_524625.3	Gene:	Eph / 43803	FlyBaseID:	FBgn0025936	Length:	1096	Species:	Drosophila melanogaster
Sequence 2:	NP_001319310.1	Gene:	YDA / 842674	AraportID:	AT1G63700	Length:	883	Species:	Arabidopsis thaliana

Alignment Length:	372	Identity:	90/372 - (24%)
Similarity:	156/372 - (41%)	Gaps:	64/372 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   664 SKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQA 728
            ::..|| :::.::.||||....||      |.|.         :|.:..:.|   |.....|.:|
plant   345 TRRLDD-NRQQSHRLPLPPLLISN------TCPF---------SPTYSAATS---PSVPRSPARA 390

  Fly   729 IREFAREIDANYITIEA------------IIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGS 781
                           ||            ::|.|.||.|..|............:|.:.:..|.|
plant   391 ---------------EATVSPGSRWKKGRLLGMGSFGHVYLGFNSESGEMCAMKEVTLCSDDPKS 440

  Fly   782 SEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLI 846
            .|.|: ....|.|::.:..|.|::...|..|..:.:.|..||:..||:...|: ..|:|....:.
plant   441 RESAQ-QLGQEISVLSRLRHQNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQ-EYGQFGENAIR 503

  Fly   847 VMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIENASDAYTTRGGKIPVRW 911
            ...:.|.||::||...|.||||:...|:||:.....|:||||:::.|...|...:.:|...   |
plant   504 NYTQQILSGLAYLHAKNTVHRDIKGANILVDPHGRVKVADFGMAKHITAQSGPLSFKGSPY---W 565

  Fly   912 TAPEAIAFRKFTS-ASDVWSYGVVLWEVMSYGERPYWN-WSNQDVIKSIEKGYRLPAPMDCPEAL 974
            .|||.|.....:: |.|:||.|..:.|:.:  .:|.|: :.....:..|.....||   |.|:.|
plant   566 MAPEVIKNSNGSNLAVDIWSLGCTVLEMAT--TKPPWSQYEGVPAMFKIGNSKELP---DIPDHL 625

  Fly   975 YQ----LMLDCWQKQRTHRPTFASIV--STLDNLARQPQSLLTTRPS 1015
            .:    .:..|.|:...:|||.|.::  :.:.|:....:.:::..|:
plant   626 SEEGKDFVRKCLQRNPANRPTAAQLLDHAFVRNVMPMERPIVSGEPA 672

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eph	NP_524625.3	EphR_LBD	85..260	CDD:198439
		FN3	387..476	CDD:238020
		FN3	536..623	CDD:238020
		EphA2_TM	644..736	CDD:291255	15/71 (21%)
		PTKc_EphR	736..1002	CDD:270629	73/285 (26%)
		Pkinase_Tyr	741..999	CDD:285015	73/277 (26%)
		SAM_1	1033..1092	CDD:278937
		SAM	1039..1092	CDD:197735
YDA	NP_001319310.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000