Protein Alignment Eph and NIK1

DIOPT Version :9

• Sequence 1: NP_524625.3
• Gene: Eph / 43803
• FlyBaseID: FBgn0025936
• Length: 1096
• Species: Drosophila melanogaster
• Sequence 2: NP_197104.1
• Gene: NIK1 / 831457
• AraportID: AT5G16000
• Length: 638
• Species: Arabidopsis thaliana
• Alignment Length: 561
• Identity: 118/561 - (21%)
• Similarity: 216/561 - (38%)
• Gaps: 146/561 - (26%)

  Fly   526 TESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAH 590
            |.|..::.:.||||:.:.|.:        ::...|.|...:     ..|:.::.|..........
plant    96 TLSPSITNLTNLRIVLLQNNN--------IKGKIPAEIGRL-----TRLETLDLSDNFFHGEIPF 147

  Fly   591 IVGLLENTEYGFQVRCKTNNGFG-----------------SYSNM------IYAQTLQSVG---- 628
            .||.|::.:|   :|...|:..|                 ||:|:      ..|:|...||
plant   148 SVGYLQSLQY---LRLNNNSLSGVFPLSLSNMTQLAFLDLSYNNLSGPVPRFAAKTFSIVGNPLI 209

  Fly   629 -----------------SVYDDSVQIRFIAG-------AIV----TGVLFLVIFIIATVYFMRSK 665
                             |:..:...:...||       ||.    .|.:.|:...:....:.|.:
plant   210 CPTGTEPDCNGTTLIPMSMNLNQTGVPLYAGGSRNHKMAIAVGSSVGTVSLIFIAVGLFLWWRQR 274

  Fly   666 HQDD--LDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQA 728
            |..:  .|.|..||                        |..|:   .||.|.:           .
plant   275 HNQNTFFDVKDGNH------------------------HEEVS---LGNLRRF-----------G 301

  Fly   729 IREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEA 793
            .||.  :|..|..:.:.::|.|.:|:|.:|.|.      ....||:|.||.|.:......|.||.
plant   302 FREL--QIATNNFSSKNLLGKGGYGNVYKGILG------DSTVVAVKRLKDGGALGGEIQFQTEV 358

  Fly   794 SIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSY 858
            .::....|.|::.|.|........:::..||.|||:.:.::.......:::..:.: |.|.|:.|
plant   359 EMISLAVHRNLLRLYGFCITQTEKLLVYPYMSNGSVASRMKAKPVLDWSIRKRIAI-GAARGLVY 422

  Fly   859 L---SDMNYVHRDLAARNVLVNAQLICKIADFGLSREIENASDAYTTRGGKIPVRWTAPEAIAFR 920
            |   .|...:|||:.|.|:|::......:.||||::.::: .|::.|...:..|...|||.::..
plant   423 LHEQCDPKIIHRDVKAANILLDDYCEAVVGDFGLAKLLDH-QDSHVTTAVRGTVGHIAPEYLSTG 486

  Fly   921 KFTSASDVWSYGVVLWEVMSYGER--PYWNWSNQ-----DVIKSIEKGYRLPAPMDCP------- 971
            :.:..:||:.:|::|.|::: |:|  .:...:||     |.:|.|.:..:|...:|..
plant   487 QSSEKTDVFGFGILLLELVT-GQRAFEFGKAANQKGVMLDWVKKIHQEKKLELLVDKELLKKKSY 550

  Fly   972 -----EALYQLMLDCWQKQRTHRPTFASIVSTL--DNLARQ 1005
                 :.:.::.|.|.|....|||..:.:|..|  |.||.:
plant   551 DEIELDEMVRVALLCTQYLPGHRPKMSEVVRMLEGDGLAEK 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eph	NP_524625.3	EphR_LBD	85..260	CDD:198439
		FN3	387..476	CDD:238020
		FN3	536..623	CDD:238020	20/109 (18%)
		EphA2_TM	644..736	CDD:291255	16/97 (16%)
		PTKc_EphR	736..1002	CDD:270629	71/289 (25%)
		Pkinase_Tyr	741..999	CDD:285015	67/279 (24%)
		SAM_1	1033..1092	CDD:278937
		SAM	1039..1092	CDD:197735
NIK1	NP_197104.1	LRRNT_2	39..78	CDD:285463
		leucine-rich repeat	107..130	CDD:275380	6/35 (17%)
		LRR_8	129..189	CDD:290566	11/62 (18%)
		leucine-rich repeat	131..154	CDD:275380	5/22 (23%)
		leucine-rich repeat	155..178	CDD:275380	4/25 (16%)
		PKc_like	318..586	CDD:304357	68/276 (25%)
		TyrKc	318..583	CDD:197581	67/273 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I1804
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050