DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eph and AT3G02880

DIOPT Version :9

Sequence 1:	NP_524625.3	Gene:	Eph / 43803	FlyBaseID:	FBgn0025936	Length:	1096	Species:	Drosophila melanogaster
Sequence 2:	NP_186938.1	Gene:	AT3G02880 / 821198	AraportID:	AT3G02880	Length:	627	Species:	Arabidopsis thaliana

Alignment Length:	425	Identity:	95/425 - (22%)
Similarity:	169/425 - (39%)	Gaps:	82/425 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   633 DSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPI 697
            |.:....|.|.::..|:.|::.::......|.:      ||..|   :|.......|.:..::..
plant   247 DKLSAGAIVGIVIGCVVGLLLLLLILFCLCRKR------KKEEN---VPSRNVEAPVAAATSSAA 302

  Fly   698 VKKLHLNVTTP--LFGNSRSYVDPHTYEDPNQAIREFAR-EIDANYITIEAIIGGGEFGDVCRGR 759
            :.|..:.|..|  ..|:....|:    :|....::.|.. ::|........::|.|..|...:.
plant   303 IPKETVVVVPPAKATGSESGAVN----KDLTFFVKSFGEFDLDGLLKASAEVLGKGTVGSSYKA- 362

  Fly   760 LKIPPNFVQDIDVAIKTLK----PGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMII 820
                 :|...:.||:|.|:    |   ||   :|.....::|...|.|::.|.......:..:::
plant   363 -----SFEHGLVVAVKRLRDVVVP---EK---EFRERLHVLGSMSHANLVTLIAYYFSRDEKLLV 416

  Fly   821 TEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASG----MSYL--SDMNYVHRDLAARNVLVNAQ 879
            .|||..|||...|..|.|..:|........|||.|    :|||  .|....|.::.:.|:|::..
plant   417 FEYMSKGSLSAILHGNKGNGRTPLNWETRAGIALGAARAISYLHSRDGTTSHGNIKSSNILLSDS 481

  Fly   880 LICKIADFGLSREIENASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGER 944
            ...|::|:||:..|.:.|......|      :.|||....||.:..:||:|:||::.|::: |:.
plant   482 YEAKVSDYGLAPIISSTSAPNRIDG------YRAPEITDARKISQKADVYSFGVLILELLT-GKS 539

  Fly   945 PYWNWSNQDVIKSIEKGYRLP----------APMDC---------PEA------LYQLMLDCWQK 984
            |.....|       |:|..||          .|.|.         ||.      |.::.:.|..:
plant   540 PTHQQLN-------EEGVDLPRWVQSVTEQQTPSDVLDPELTRYQPEGNENIIRLLKIGMSCTAQ 597

  Fly   985 QRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESD 1019
            ....||:.|.:...::.::....|     |:|.||
plant   598 FPDSRPSMAEVTRLIEEVSHSSGS-----PNPVSD 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eph	NP_524625.3	EphR_LBD	85..260	CDD:198439
		FN3	387..476	CDD:238020
		FN3	536..623	CDD:238020
		EphA2_TM	644..736	CDD:291255	15/94 (16%)
		PTKc_EphR	736..1002	CDD:270629	72/300 (24%)
		Pkinase_Tyr	741..999	CDD:285015	71/292 (24%)
		SAM_1	1033..1092	CDD:278937
		SAM	1039..1092	CDD:197735
AT3G02880	NP_186938.1	LRRNT_2	26..63	CDD:400522
		PLN00113	<62..621	CDD:215061	90/412 (22%)
		leucine-rich repeat	92..115	CDD:275380
		leucine-rich repeat	116..139	CDD:275380
		leucine-rich repeat	140..163	CDD:275380
		leucine-rich repeat	164..183	CDD:275380
		leucine-rich repeat	185..208	CDD:275380
		PKc_like	351..614	CDD:419665	71/288 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I1804
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050