DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eph and AT2G26730

DIOPT Version :9

Sequence 1:	NP_524625.3	Gene:	Eph / 43803	FlyBaseID:	FBgn0025936	Length:	1096	Species:	Drosophila melanogaster
Sequence 2:	NP_180241.1	Gene:	AT2G26730 / 817214	AraportID:	AT2G26730	Length:	658	Species:	Arabidopsis thaliana

Alignment Length:	420	Identity:	91/420 - (21%)
Similarity:	168/420 - (40%)	Gaps:	79/420 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   643 AIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTT 707
            ||:.....:.:.::|.:.|:..:.:...::..|.. |.|...|:..|   |..|........||.
plant   260 AIIVASALVALLLLALLLFLCLRKRRGSNEARTKQ-PKPAGVATRNV---DLPPGASSSKEEVTG 320

  Fly   708 PLFG-------NSRSYVDPHTYE-DPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPP 764
            ...|       |...:.:...|. |....:|..|.           ::|.|..|...:..|:
plant   321 TSSGMGGETERNKLVFTEGGVYSFDLEDLLRASAE-----------VLGKGSVGTSYKAVLE--- 371

  Fly   765 NFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSL 829
               :...|.:|.||...:.|.  :|.|:..::|:..|||||.|:......:..:::.::|..|||
plant   372 ---EGTTVVVKRLKDVMASKK--EFETQMEVVGKIKHPNVIPLRAYYYSKDEKLLVFDFMPTGSL 431

  Fly   830 DTFLRVNDGKFQT-------LQLIVMLRGIASGMSYLS-DMNYVHRDLAARNVLVNAQLICKIAD 886
            ...|..:.|..:|       :::.:.   .|.|:::|. ....||.::.|.|:|::......::|
plant   432 SALLHGSRGSGRTPLDWDNRMRIAIT---AARGLAHLHVSAKLVHGNIKASNILLHPNQDTCVSD 493

  Fly   887 FGLSREIENASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVM--------SYGE 943
            :||::...|:|......|      :.|||.:..||.|..|||:|:||:|.|::        |.||
plant   494 YGLNQLFSNSSPPNRLAG------YHAPEVLETRKVTFKSDVYSFGVLLLELLTGKSPNQASLGE 552

  Fly   944 R----PYW-------NWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVS 997
            .    |.|       .|:.:.....:.:.:.:...|   ..|.|:.:.|.......||....::.
plant   553 EGIDLPRWVLSVVREEWTAEVFDVELMRYHNIEEEM---VQLLQIAMACVSTVPDQRPVMQEVLR 614

  Fly   998 TLDNLARQP-------QSLLTTRPSPESDG 1020
            .::::.|..       ||  :..||..|:|
plant   615 MIEDVNRSETTDDGLRQS--SDDPSKGSEG 642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eph	NP_524625.3	EphR_LBD	85..260	CDD:198439
		FN3	387..476	CDD:238020
		FN3	536..623	CDD:238020
		EphA2_TM	644..736	CDD:291255	18/99 (18%)
		PTKc_EphR	736..1002	CDD:270629	65/292 (22%)
		Pkinase_Tyr	741..999	CDD:285015	65/284 (23%)
		SAM_1	1033..1092	CDD:278937
		SAM	1039..1092	CDD:197735
AT2G26730	NP_180241.1	LRRNT_2	28..62	CDD:400522
		PLN00113	<67..625	CDD:215061	85/399 (21%)
		leucine-rich repeat	68..92	CDD:275380
		leucine-rich repeat	93..116	CDD:275380
		leucine-rich repeat	117..140	CDD:275380
		leucine-rich repeat	141..164	CDD:275380
		leucine-rich repeat	165..186	CDD:275380
		STKc_IRAK	357..617	CDD:270968	65/279 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I1804
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050