Sequence 1: | NP_524625.3 | Gene: | Eph / 43803 | FlyBaseID: | FBgn0025936 | Length: | 1096 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_068713.2 | Gene: | AXL / 558 | HGNCID: | 905 | Length: | 894 | Species: | Homo sapiens |
Alignment Length: | 928 | Identity: | 227/928 - (24%) |
---|---|---|---|
Similarity: | 354/928 - (38%) | Gaps: | 236/928 - (25%) |
- Green bases have known domain annotations that are detailed below.
Fly 171 PGNALSCKETFSLLFYEFDAATREPPP--WQTDSYRL------IARIAAGEGRFNQNSD--VDIN 225
Fly 226 TEVKSIAVNKKGVYFAFRDQGACISVLAVKVYYITCPAVT--ENFAHFNETPTGREITIIEKQNG 288
Fly 289 TCVDNAEPYETPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTF--KSPEVTKCTPC 351
Fly 352 PPNSNASKTGSPFCKC--ASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNE 414
Fly 415 SFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTD--TFNETKITLTNLEPVTTYTVQIHAINSV 477
Fly 478 SHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNE-VKTGQAEIVFTTESVLLSTVFNLRILA 541
Fly 542 ITNKDADLEWDKPVQSDFPLE--------FYEVRWFPKVELDAINKSALNTKETKAHIVGLLENT 598
Fly 599 EYGFQVRCKTNNGFGSYSNM---IYAQT--------------------LQSVGSVYDDSVQIRF- 639
Fly 640 ------IAGAIVTG--VLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTP 696
Fly 697 IVKKLHLNVTTPLFGNSRSYVDPHTYEDPN-----QAIREFARE--IDANYITIEAIIGGGEFGD 754
Fly 755 VCRGRLKIPPNFVQD---IDVAIKTLKPGSSEKARC-DFLTEASIMGQFDHPNVIYLQGVVTRSN 815
Fly 816 -------PVMIITEYMENGSLDTFL---RVNDGK--FQTLQLIVMLRGIASGMSYLSDMNYVHRD 868
Fly 869 LAARNVLVNAQLICKIADFGLSREIENASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGV 933
Fly 934 VLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVST 998
Fly 999 LDNL------ARQPQSLL 1010 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Eph | NP_524625.3 | EphR_LBD | 85..260 | CDD:198439 | 19/98 (19%) |
FN3 | 387..476 | CDD:238020 | 18/90 (20%) | ||
FN3 | 536..623 | CDD:238020 | 18/97 (19%) | ||
EphA2_TM | 644..736 | CDD:291255 | 21/100 (21%) | ||
PTKc_EphR | 736..1002 | CDD:270629 | 108/281 (38%) | ||
Pkinase_Tyr | 741..999 | CDD:285015 | 106/273 (39%) | ||
SAM_1 | 1033..1092 | CDD:278937 | |||
SAM | 1039..1092 | CDD:197735 | |||
AXL | NP_068713.2 | interaction with Gas6 | 26..92 | 12/54 (22%) | |
Ig | 53..119 | CDD:319273 | 15/76 (20%) | ||
Ig2_Axl_Tyro3_like | 141..222 | CDD:143226 | 22/116 (19%) | ||
FN3 | 225..328 | CDD:238020 | 22/126 (17%) | ||
fn3 | 335..418 | CDD:306538 | 22/123 (18%) | ||
PTKc_Axl | 535..811 | CDD:270660 | 108/282 (38%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |