Protein Alignment Eph and Src42A

DIOPT Version :10

• Sequence 1: NP_524625.3
• Gene: Eph / 43803
• FlyBaseID: FBgn0025936
• Length: 1096
• Species: Drosophila melanogaster
• Sequence 2: NP_001400996.1
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1606
• Species: Drosophila melanogaster
• Alignment Length: 278
• Identity: 123/278 - (44%)
• Similarity: 168/278 - (60%)
• Gaps: 14/278 - (5%)

  Fly   735 EIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQF 799
            |||...:.....:|.|:||||..|.      :.....|||||||.|:.:..  |||.||.||.:.
  Fly  1331 EIDRTSLKFVRKLGSGQFGDVWEGL------WNNTTPVAIKTLKSGTMDPK--DFLAEAQIMKKL 1387

  Fly   800 DHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQ---LIVMLRGIASGMSYLSD 861
            .|..:|.|..|.|...|:.||||.|::|||..:|:...||.::|:   ||.|...||:||:||..
  Fly  1388 RHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLES 1452

  Fly   862 MNYVHRDLAARNVLVNAQLICKIADFGLSREIENASDAYTTR-GGKIPVRWTAPEAIAFRKFTSA 925
            .||:|||||||||||....|.|||||||:|.|:  .|.|..| |.:.|::||||||..:.||:..
  Fly  1453 QNYIHRDLAARNVLVGDGNIVKIADFGLARLIK--EDEYEARVGARFPIKWTAPEAANYSKFSIK 1515

  Fly   926 SDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRP 990
            |||||:|::|.|:::||..||...:|.:|:..:|.|||:|.|.:|...||::||:||.|....||
  Fly  1516 SDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRP 1580

  Fly   991 TFASIVSTLDNLARQPQS 1008
            ||.::...|::.....||
  Fly  1581 TFETLQWKLEDFYTSDQS 1598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eph	NP_524625.3	EphR_LBD	85..260	CDD:198439
		FN3	387..476	CDD:238020
		FN3	536..623	CDD:238020
		EphA2_TM	640..738	CDD:464211	2/2 (100%)
		PTKc_EphR	736..1002	CDD:270629	120/269 (45%)
		SAM_1	1029..1092	CDD:425739
Src42A	NP_001400996.1	SH2_Src_Src42	1210..1301	CDD:198233
		PTKc_Frk_like	1328..1596	CDD:270653	121/274 (44%)