Protein Alignment Eph and LOC108645842

DIOPT Version :9

• Sequence 1: NP_524625.3
• Gene: Eph / 43803
• FlyBaseID: FBgn0025936
• Length: 1096
• Species: Drosophila melanogaster
• Sequence 2: XP_031752075.1
• Gene: LOC108645842 / 108645842
• -ID: -
• Length: 558
• Species: Xenopus tropicalis
• Alignment Length: 567
• Identity: 235/567 - (41%)
• Similarity: 327/567 - (57%)
• Gaps: 48/567 - (8%)

  Fly   531 LSTVFNLRILAITNKDADLEWDKPVQSDFPL---EFYEVRWFPKVELDAINKSALNTKETKAHIV 592
            ||.:.::|...|..|...|.|..|.   ||.   ..||::::.|.:.|. :.|.:.|..|...:.
 Frog     9 LSLITDIRADKIDQKRITLSWQDPA---FPFINNTEYEIKYYEKDQRDQ-SYSTVRTPLTTVTVY 69

  Fly   593 GLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIA 657
            .|...|.|.||:|..::..|.|||..|..:||..:..|..:...:..|....|.|.:.|:..::.
 Frog    70 NLKPGTVYVFQIRTSSSQDFSSYSPTIEVETLGELALVSTEQNPLIIIVIVSVAGFIVLLSMVVG 134

  Fly   658 TVYFMR----SKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVD 718
            .:.:.|    ||...|.|::...|..:|                              ..|:|:|
 Frog   135 LMIWRRQCGYSKASQDGDEELYFHFKIP------------------------------TRRTYID 169

  Fly   719 PHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSE 783
            |.|.|||.||:..||:|:|.:.|.||.|:|.|::|:||:|.||:|..  :::.|||:||:.|.||
 Frog   170 PDTCEDPMQAVHLFAKELDNSCIKIERILGTGDYGEVCKGCLKLPSK--RELPVAIQTLRAGCSE 232

  Fly   784 KARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVM 848
            |.:..||.||||||||||||:|.|:||:||.|.:|.:.||:.||.||:|:|.|||:....|||.|
 Frog   233 KQKRAFLAEASIMGQFDHPNIIRLEGVITRGNTMMTVMEYLGNGVLDSFVRKNDGQLTVPQLIGM 297

  Fly   849 LRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIENASDAYTTRGGKIPVRWTA 913
            |.||||||.||::|:|:|:.|||..:|||:.|:|||:.|...:| :.....::|.|||..|.|||
 Frog   298 LTGIASGMKYLTEMSYIHKCLAANKILVNSNLVCKISGFRQMQE-DKLDTIFSTMGGKSTVLWTA 361

  Fly   914 PEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLM 978
            ||||.:.::::||||||:|:|:||||||||||||:.|||||||:||.|:|||||:.||..|:|||
 Frog   362 PEAIQYHRYSTASDVWSFGIVMWEVMSYGERPYWDMSNQDVIKAIEDGFRLPAPISCPPYLHQLM 426

  Fly   979 LDCWQKQRTHRPTFASIVSTLDNLARQP-QSLLTTRPSPESDGNHILDGQRGQNIFISTDL---W 1039
            ||||||.|..||.|..|.|.|....:.| :|..||.....|....|...:|....|.|.:.   |
 Frog   427 LDCWQKDRNERPKFTHIHSILSKHGQSPDKSKSTTSTINRSHSTSIPLIERTFTTFPSFNSVGEW 491

  Fly  1040 LEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKIL 1086
            ||.|:|.||..:|..|.....:.::|:|.|.:..:|||.|.|||.||
 Frog   492 LEAIEMERYKDNFTAAGYCYLESVARMTVQDVMSLGITSVEHQKTIL 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eph	NP_524625.3	EphR_LBD	85..260	CDD:198439
		FN3	387..476	CDD:238020
		FN3	536..623	CDD:238020	26/89 (29%)
		EphA2_TM	644..736	CDD:291255	22/95 (23%)
		PTKc_EphR	736..1002	CDD:270629	150/265 (57%)
		Pkinase_Tyr	741..999	CDD:285015	148/257 (58%)
		SAM_1	1033..1092	CDD:278937	23/57 (40%)
		SAM	1039..1092	CDD:197735	21/48 (44%)
LOC108645842	XP_031752075.1	FN3	13..100	CDD:238020	26/90 (29%)
		EphA2_TM	117..188	CDD:405290	24/100 (24%)
		PKc_like	186..449	CDD:419665	151/265 (57%)
		SAM_EPH-A10	479..548	CDD:188948	23/60 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D397694at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010