Protein Alignment Eph and ltk

DIOPT Version :10

• Sequence 1: NP_524625.3
• Gene: Eph / 43803
• FlyBaseID: FBgn0025936
• Length: 1096
• Species: Drosophila melanogaster
• Sequence 2: XP_002933782.3
• Gene: ltk / 100498306
• XenbaseID: XB-GENE-22068681
• Length: 1314
• Species: Xenopus tropicalis
• Alignment Length: 464
• Identity: 135/464 - (29%)
• Similarity: 220/464 - (47%)
• Gaps: 66/464 - (14%)

  Fly   632 DDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTP 696
            :..:.:..|...::..|:..:||...::.|:..:.:..|:              ...|....|..
 Frog   826 EKQLPLSLILAVLIATVILGIIFACGSLSFVYHRKKKQLE--------------GARVRLQSTEY 876

  Fly   697 IVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGR-- 759
            .:.|:..::.      ...|...:.:.....::.|. :|:....||:...:|.|.||:|..|.
 Frog   877 KLSKIRSSII------MTDYNPNYCFAGKGASLSEL-KEVPRKNITLLRALGHGAFGEVYEGMVV 934

  Fly   760 -LKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEY 823
             :...||.:|   ||||||....||:...|||.||.|:.:|.|.|::...||..::.|..|:.|.
 Frog   935 GISGDPNPLQ---VAIKTLPEICSEQDEMDFLMEALIISKFSHQNIVRCIGVSLQTLPRFILLEL 996

  Fly   824 MENGSLDTFLRVN------DGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLV---NAQ 879
            |..|.:.:|||.|      ......|.|:.|.|.||.|..||.:.:::|||:||||.|:   ...
 Frog   997 MSGGDMKSFLRQNRPWINQPSTLSMLDLLNMARDIACGCKYLEENHFIHRDIAARNCLLTYSGTG 1061

  Fly   880 LICKIADFGLSREIENASDAYTTRGGK--IPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYG 942
            .:.||.|||::|:|..||  |..:||:  :||:|..|||.....|||.:|.||:||:|||:.|.|
 Frog  1062 RVAKIGDFGMARDIYRAS--YYRKGGRAMLPVKWMPPEAFLEGVFTSKTDTWSFGVLLWEIFSLG 1124

  Fly   943 ERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQ 1007
            ..||...:||:|::.:..|.|:..|.:||..:|::|..|||....|||.|::|:..:....:.|.
 Frog  1125 YMPYPCKTNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHTPEHRPNFSTILERISYCTQDPD 1189

  Fly  1008 SLLT-----TRPSPESDGNHIL--DGQRGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISR 1065
            .:.|     :.|:||.:|:..:  :...|.|..:|:.               ..|.|::.|.
 Frog  1190 VINTPLPVESGPAPEDEGSTSIRPNSCNGLNPIMSSQ---------------PIAPLLDTQS--- 1236

  Fly  1066 LTAQQLSDM 1074
             |.|:|.|:
 Frog  1237 -TEQKLGDV 1244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eph	NP_524625.3	EphR_LBD	85..260	CDD:198439
		FN3	387..476	CDD:238020
		FN3	536..623	CDD:238020
		EphA2_TM	640..738	CDD:464211	12/97 (12%)
		PTKc_EphR	736..1002	CDD:270629	107/279 (38%)
		SAM_1	1029..1092	CDD:425739	10/46 (22%)
ltk	XP_002933782.3	LDLa	230..263	CDD:197566
		MAM	277..431	CDD:99706
		PTKc_ALK_LTK	907..1183	CDD:270632	108/280 (39%)