Protein Alignment Eph and epha10

DIOPT Version :10

• Sequence 1: NP_524625.3
• Gene: Eph / 43803
• FlyBaseID: FBgn0025936
• Length: 1096
• Species: Drosophila melanogaster
• Sequence 2: NP_001090817.1
• Gene: epha10 / 100037915
• XenbaseID: XB-GENE-5893530
• Length: 281
• Species: Xenopus tropicalis
• Alignment Length: 268
• Identity: 99/268 - (36%)
• Similarity: 146/268 - (54%)
• Gaps: 36/268 - (13%)

  Fly    82 ADQVVLLDTTR-EATLEWTRYPYGPQAQTPGWVEESFTD-FVKGINWRSYVVCDVAYHNVNNWLW 144
            |:||:|||:.. :|.|.||.:|      :.||.|.|..| ..|.|  |:|.||:|...|.||||.
 Frog    21 AEQVILLDSKESQAELGWTSHP------SNGWEEISGVDENYKPI--RTYQVCNVMEPNQNNWLQ 77

  Fly   145 SPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLF----YEFDAATREPPPWQTDSYRL 205
            :.:|.|.:..|::||::||:|||:..||.|.:|||||:|.:    |:.....:|      ..|..
 Frog    78 TGWILRRNGQRIFIELKFTLRDCNSIPGVAGTCKETFNLYYIESDYDLGRNIKE------SKYVK 136

  Fly   206 IARIAAGEGRFNQNS----DVDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVT 265
            |..|||.|. |.|..    .:.:||||:.|. :||||.:..|:|.|||:::::|:|||..|.:..
 Frog   137 IDTIAADES-FTQGDLGERKMKLNTEVREIGHLNKKGFHLGFQDVGACVALVSVRVYYKKCLSTV 200

  Fly   266 ENFAHFNETPTGREITIIEKQNGTCVDNAE-----PYETPTYLCKGDGKWTILTGGCRCKAGYEP 325
            :|.|.|.:|......:.:.:..||||:|:|     |   |...|..:|:|.:..|.|.|.||:|.
 Frog   201 QNLAVFPDTVAEAAFSTLVEVRGTCVNNSEVDLDNP---PRMHCSAEGEWLVPIGKCTCSAGFEE 262

  Fly   326 NYTNKTCT 333
            .  ..:||
 Frog   263 K--EGSCT 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eph	NP_524625.3	EphR_LBD	85..260	CDD:198439	73/185 (39%)
		FN3	387..476	CDD:238020
		FN3	536..623	CDD:238020
		EphA2_TM	640..738	CDD:464211
		PTKc_EphR	736..1002	CDD:270629
		SAM_1	1029..1092	CDD:425739
epha10	NP_001090817.1	EphR_LBD	23..195	CDD:470656	74/186 (40%)