Protein Alignment CG17698 and Stk11

DIOPT Version :10

• Sequence 1: NP_001036633.2
• Gene: CG17698 / 4379919
• FlyBaseID: FBgn0040056
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_001101539.1
• Gene: Stk11 / 314621
• RGDID: 1308653
• Length: 436
• Species: Rattus norvegicus
• Alignment Length: 424
• Identity: 124/424 - (29%)
• Similarity: 190/424 - (44%)
• Gaps: 98/424 - (23%)

  Fly   280 LNQYRLMEQIGQGSYGLVKLAYSEEDSTHYAMKILSKKRLLRQAGLMRRGPRKATSPLDRVYREI 344
            :.:|.:.:.:|:||||.||.....|.....|:|||.||:|       ||.|....:    |.:||
  Rat    46 IGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKL-------RRIPNGEAN----VKKEI 99

  Fly   345 AVLKKLDHPNVVKLVEVLDDPLEDSLYMVFELVKQG--EVLRIPTDNPLSEKR-----AWSIFRE 402
            .:|::|.|.||::||:||.:..:..:|||.|....|  |:|     :.:.|||     |...||:
  Rat   100 QLLRRLRHRNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEML-----DSVPEKRFPVCQAHGYFRQ 159

  Fly   403 SLLGLEYYTMLSSSAISLKRIFVYTVHHQKIIHADIKPGNLLLTEFGHVKIADLGVC---NEFLG 464
            .:.||||                  :|.|.|:|.||||||||||..|.:||:||||.   :.|..
  Rat   160 LIDGLEY------------------LHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAV 206

  Fly   465 DDATISNGSTAGTPAFRAPETLIPGQNEYCGRAADVWALGATLYSLIFGNVPFLADSVPLLYEKI 529
            ||..   .::.|:|||:.|| :..|.:.:.|...|:|:.|.|||::..|..||..|::..|:|.|
  Rat   207 DDTC---RTSQGSPAFQPPE-IANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENI 267

  Fly   530 KQDSVKFPENHKVTENLKSCIVQMLEKNPTQRITIPQLKTSKWV-----TSDGDYPLP------- 582
            .:.....|.:  ....|...:..|||..|.:|.:|.|::...|.     .::...|:|
  Rat   268 GRGDFTIPCD--CAPPLSDLLRGMLEYEPAKRFSIRQIRQHSWFRKKHPLAEALVPIPPSPDTKD 330

  Fly   583 -----------------TEEENCCLVQVDDEDIDSVVRSIPKLDTLILIKTMLKK--------HS 622
                             .|||       :|||:..:...|.......:...:|::        ||
  Rat   331 RWRSMTVVPYLEDLHGRAEEE-------EDEDLFDIEDGIIYTQDFTVPGQVLEEEVGQNGQSHS 388

  Fly   623 FGNPFVKGCSGTSSSLAGCSRIERFIRAGRSNSA 656
            .  |.....:||...|:  |:::...|.|.:|.|
  Rat   389 L--PKAVCVNGTEPQLS--SKVKPEGRPGAANPA 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17698	NP_001036633.2	STKc_CAMKK	288..574	CDD:271020	102/300 (34%)
Stk11	NP_001101539.1	Sufficient for interaction with SIRT1. /evidence=ECO:0000250	45..90		18/50 (36%)
		STKc_LKB1	55..309	CDD:271021	101/293 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421		8/24 (33%)