DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17698 and Camkk2

DIOPT Version :9

Sequence 1:	NP_001036633.2	Gene:	CG17698 / 4379919	FlyBaseID:	FBgn0040056	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	XP_006530293.1	Gene:	Camkk2 / 207565	MGIID:	2444812	Length:	625	Species:	Mus musculus

Alignment Length:	509	Identity:	233/509 - (45%)
Similarity:	312/509 - (61%)	Gaps:	70/509 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 DSESNKPNKMKKCLDYESVKRYPCKVSNEPPQHNTASKPQIL-YETRPIYPNVPYSPYSTPFSSP 254
            |.||..|...:|.    |::        ||.|...||....| ...|.|.|::.|||.|:|.|||
Mouse    86 DPESRSPLSGRKM----SLQ--------EPSQGGPASSSNSLDMNGRCICPSLSYSPASSPQSSP 138

  Fly   255 RSSRRKPAFRESRRISIDKSGSFLQLNQYRLMEQIGQGSYGLVKLAYSEEDSTHYAMKILSKKRL 319
            |..||...  ||..:||......:|||||.|.::||:||||:|||||:|.|:|:||||:||||:|
Mouse   139 RMPRRPTV--ESHHVSITGLQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKL 201

  Fly   320 LRQAGLMRRGPRKAT-----------SPLDRVYREIAVLKKLDHPNVVKLVEVLDDPLEDSLYMV 373
            :||||..||.|.:..           .|:::||:|||:|||||||||||||||||||.||.||||
Mouse   202 IRQAGFPRRPPPRGARPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMV 266

  Fly   374 FELVKQGEVLRIPTDNPLSEKRAWSIFRESLLGLEYYTMLSSSAISLKRIFVYTVHHQKIIHADI 438
            ||||.||.|:.:||..||||.:|...|::.:.|:||                  :|:|||||.||
Mouse   267 FELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEY------------------LHYQKIIHRDI 313

  Fly   439 KPGNLLLTEFGHVKIADLGVCNEFLGDDATISNGSTAGTPAFRAPETLIPGQNEYCGRAADVWAL 503
            ||.|||:.|.||:||||.||.|||.|.||.:||  |.|||||.|||:|...:..:.|:|.||||:
Mouse   314 KPSNLLVGEDGHIKIADFGVSNEFKGSDALLSN--TVGTPAFMAPESLSETRKIFSGKALDVWAM 376

  Fly   504 GATLYSLIFGNVPFLADSVPLLYEKIKQDSVKFPENHKVTENLKSCIVQMLEKNPTQRITIPQLK 568
            |.|||..:||..||:.:.:..|:.|||..:::||:...:.|:||..|.:||:|||..||.:|::|
Mouse   377 GVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIK 441

  Fly   569 TSKWVTSDGDYPLPTEEENCCLVQVDDEDIDSVVRSIPKLDTLILIKTMLKKHSFGNPFVKGCSG 633
            ...|||..|..|||:|:|||.||:|.:|::::.|:.||.|.|:||:|||::|.||||||
Mouse   442 LHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPF------ 500

  Fly   634 TSSSLAGCSRIERFIRAGRSNSAPGSYHMSTAR-----QPSSDTLLPSLMEHCS 682
                 .|..|.|      ||.||||  ::.|.:     :|.|:..:.:.:..|:
Mouse   501 -----EGSRREE------RSLSAPG--NLLTKKPTREWEPLSEPKVNACLPACA 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17698	NP_001036633.2	S_TKc	283..573	CDD:214567	154/300 (51%)
CG17698	NP_001036633.2	STKc_CAMKK	288..574	CDD:271020	153/296 (52%)
Camkk2	XP_006530293.1	PKc_like	162..447	CDD:389743	158/304 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	161	1.000	Domainoid score	I3993
eggNOG	1	0.900	-	-		E1_KOG0585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	408	1.000	Inparanoid score	I1858
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001468
OrthoInspector	1	1.000	-	-		otm44057
orthoMCL	1	0.900	-	-		OOG6_100881
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1033
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.720