DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17698 and camkk2

DIOPT Version :9

Sequence 1:	NP_001036633.2	Gene:	CG17698 / 4379919	FlyBaseID:	FBgn0040056	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	XP_002937747.1	Gene:	camkk2 / 100135108	XenbaseID:	XB-GENE-990544	Length:	558	Species:	Xenopus tropicalis

Alignment Length:	511	Identity:	236/511 - (46%)
Similarity:	323/511 - (63%)	Gaps:	61/511 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 TDIHK-----CVVDSESNKPNKMKKCLDYESVKRYPCKVS-NEPPQHNTASKPQILYETRPIYPN 241
            ||:|:     |.:|.....|...|.|....::...  |:| .|..|...||...:....|.|||:
Frog    80 TDLHRINESECKLDDRKVLPVGRKDCKGKLNMTNR--KLSLQERSQSTPASSNSLGMNGRYIYPS 142

  Fly   242 VPYSPYSTPFSSPRSSRRKPAFRESRRISIDKSGSFLQLNQYRLMEQIGQGSYGLVKLAYSEEDS 306
            :||||.::|.||||..||...  ||.|:||......:|||||:|.::||:||||:|||||:|:|:
Frog   143 LPYSPVTSPQSSPRLPRRPTV--ESHRVSITGCQDCVQLNQYQLKDEIGKGSYGVVKLAYNEDDN 205

  Fly   307 THYAMKILSKKRLLRQAGLMRRGPRK-----------ATSPLDRVYREIAVLKKLDHPNVVKLVE 360
            |:||||:||||:|:||||..||.|.:           |..|::|||:|||:|:||||||||||:|
Frog   206 TYYAMKVLSKKKLMRQAGFPRRPPPRGAKTATEGGVQAMGPIERVYQEIAILRKLDHPNVVKLIE 270

  Fly   361 VLDDPLEDSLYMVFELVKQGEVLRIPTDNPLSEKRAWSIFRESLLGLEYYTMLSSSAISLKRIFV 425
            |||||.||.||||||||::|.|:.:||..||:|.:|...|::.:.|:||
Frog   271 VLDDPSEDHLYMVFELVRRGPVMDVPTTKPLTEDQARFYFQDLIKGIEY---------------- 319

  Fly   426 YTVHHQKIIHADIKPGNLLLTEFGHVKIADLGVCNEFLGDDATISNGSTAGTPAFRAPETLIPGQ 490
              :|:|||||.|:||.||||.|.||:||||.||.|.|.|:||.:||  |.|||||.|||||...:
Frog   320 --LHYQKIIHRDVKPSNLLLGEDGHIKIADFGVSNTFEGNDAFLSN--TVGTPAFMAPETLSETR 380

  Fly   491 NEYCGRAADVWALGATLYSLIFGNVPFLADSVPLLYEKIKQDSVKFPENHKVTENLKSCIVQMLE 555
            ..:.|:|.||||:|.||...:||..||:.:.:..|:.|||...::||:.|.::|:||..::.||:
Frog   381 KIFSGKALDVWAMGVTLNCFVFGQCPFMDERILALHSKIKNQPLEFPDQHDISEDLKDLLLHMLD 445

  Fly   556 KNPTQRITIPQLKTSKWVTSDGDYPLPTEEENCCLVQVDDEDIDSVVRSIPKLDTLILIKTMLKK 620
            |||..||::|:||...|||..|..|||||:|||.||:|.:|::::.::.||.|.|:||:|:||:|
Frog   446 KNPESRISVPELKLHPWVTKQGLEPLPTEDENCTLVEVTEEEVENSIKHIPSLATVILVKSMLRK 510

  Fly   621 HSFGNPFVKGCSGTSSSLAGCSRIERFIRAGRSNSAPGSYHMSTARQPSSDTLLPS 676
            .|||||| :|           ||.|.     ||.|:||:..|.   |.|.::|..|
Frog   511 RSFGNPF-EG-----------SRKEE-----RSMSSPGNLLMI---QGSEESLRES 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17698	NP_001036633.2	S_TKc	283..573	CDD:214567	152/300 (51%)
CG17698	NP_001036633.2	STKc_CAMKK	288..574	CDD:271020	151/296 (51%)
camkk2	XP_002937747.1	STKc_CaMKK2	179..464	CDD:271101	156/304 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	164	1.000	Domainoid score	I3892
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	420	1.000	Inparanoid score	I1756
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D856506at2759
OrthoFinder	1	1.000	-	-		FOG0001468
OrthoInspector	1	1.000	-	-		otm49231
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1033
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060