Protein Alignment Mkp and SSH2

DIOPT Version :10

• Sequence 1: NP_001036572.1
• Gene: Mkp / 4379907
• FlyBaseID: FBgn0083992
• Length: 203
• Species: Drosophila melanogaster
• Sequence 2: NP_001269058.1
• Gene: SSH2 / 85464
• HGNCID: 30580
• Length: 1450
• Species: Homo sapiens
• Alignment Length: 139
• Identity: 42/139 - (30%)
• Similarity: 68/139 - (48%)
• Gaps: 21/139 - (15%)

  Fly    72 DFLYLGSQ-DAVSADNIIKYKITHILSVGIQTPEVEWPLPVNCTFLP---------CLDLPETNL 126
            :.::|||: :|.:.:::....:.:||:|   |.|::       .|.|         ..|...|:|
Human   340 EHVFLGSEWNASNLEDLQNRGVRYILNV---TREID-------NFFPGVFEYHNIRVYDEEATDL 394

  Fly   127 MNYILPASMEFIEDAHRSQGCVLVHCNAGVSRSPSVVIGYLMQRRDMCYEDAYNLVKSWRPCIQP 191
            :.| ...:.:||..|.:.....||||..|||||.|.||.|.|:......:.||:.||..|...:|
Human   395 LAY-WNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKP 458

  Fly   192 NAGFIQQLK 200
            |..|::||:
Human   459 NPSFMRQLE 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp	NP_001036572.1	DSP	66..201	CDD:350348	42/139 (30%)
SSH2	NP_001269058.1	SSH-N	38..263	CDD:212166
		DEK_C	277..329	CDD:462592
		DSP_slingshot_2	332..475	CDD:350417	42/139 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	644..668
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	691..711
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	723..755
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	824..852
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	867..889
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	904..981
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	989..1008
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1046..1068
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1097..1135
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1171..1206